Evidence map›Paper›PMID 38972972›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2024

Comparison of synthesized and acquired high b-value diffusion-weighted MRI for detection of prostate cancer.

Karoline Kallis, Christopher C Conlin, Allison Y Zhong, Troy S Hussain, Aritrick Chatterjee, Gregory S Karczmar, Rebecca Rakow-Penner, Anders M Dale, Tyler M Seibert

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Karoline KallisDepartment of Radiation Medicine and Applied Sciences, University of California San Diego Health, La Jolla, CA, USA.
Christopher C ConlinDepartment of Radiology, University of California San Diego Health, La Jolla, San Diego, CA, USA.
Allison Y ZhongDepartment of Radiation Medicine and Applied Sciences, University of California San Diego Health, La Jolla, CA, USA.
Troy S HussainDepartment of Radiation Medicine and Applied Sciences, University of California San Diego Health, La Jolla, CA, USA.
Aritrick ChatterjeeDepartment of Radiology, University of Chicago, Chicago, IL, USA.
Gregory S KarczmarDepartment of Radiology, University of Chicago, Chicago, IL, USA.
Rebecca Rakow-PennerDepartment of Radiology, University of California San Diego Health, La Jolla, San Diego, CA, USA.
Anders M DaleDepartment of Radiology, University of California San Diego Health, La Jolla, San Diego, CA, USA.
Tyler M SeibertDepartment of Radiology, University of California San Diego Health, La Jolla, San Diego, CA, USA. tseibert@health.ucsd.edu.ORCID http://orcid.org/0000-0002-4089-7399

Funding

San Diego Clinical and Translational Research InstituteUL1TR000100 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2012 to 2015
$19.7M
Foundation for the National Institutes of Health NIH/NIBIB K08EB026503Foundation for the National Institutes of Health NIH UL1TR000100NCATS NIH HHS UL1 TR000100
6 · The paper itself

Abstract

backgroundHigh b-value diffusion-weighted images (DWI) are used for detection of clinically significant prostate cancer (csPCa). This study qualitatively and quantitatively compares synthesized DWI (sDWI) to acquired (aDWI) for detection of csPCa.

methodsOne hundred fifty-one consecutive patients who underwent prostate MRI and biopsy were included in the study. Axial DWI with b = 0, 500, 1000, and 2000 s/mm

resultsWithin the prostate, mean ± standard deviation of percent mean differences between sDWI and aDWI signal were -46 ± 35% for sDWI

conclusionsDWI is qualitatively comparable to aDWI within the prostate. However, hyperintense artifacts are introduced with sDWI in the surrounding pelvic tissue that interfere with quantitative cancer detection and might mask metastases. In the prostate, RSIrs yields superior quantitative csPCa detection than sDWI or aDWI.

Indexed as

Diffusion Magnetic Resonance ImagingProstatic NeoplasmsAgedAged, 80 and overHumansMaleMiddle AgedProstateRetrospective StudiesDiffusion-weighted imagingProstate cancerRestricted Spectrum ImagingSynthetic high b-values

Identifiers

PMID38972972
PMCPMC11229343

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.