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ArticleInternational ophthalmology2024

Coefficient of spatial variance of choroidal thickness on swept-source optical coherence tomography in healthy eyes.

Zehua Jiang, Tian Lin, Aidi Lin, Jianwei Lin, Shirong Chen, Lingling Zhou, Haoyu Chen

Abstract read
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In one paragraph

Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zehua JiangJoint Shantou International Eye Centre of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.ORCID http://orcid.org/0000-0001-9100-0986
Tian LinJoint Shantou International Eye Centre of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.ORCID http://orcid.org/0000-0002-6415-5381
Aidi LinJoint Shantou International Eye Centre of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.ORCID http://orcid.org/0000-0002-2214-7957
Jianwei LinJoint Shantou International Eye Centre of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.ORCID http://orcid.org/0000-0001-5712-1581
Shirong ChenJoint Shantou International Eye Centre of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.ORCID http://orcid.org/0000-0002-0965-791X
Lingling ZhouJoint Shantou International Eye Centre of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.ORCID http://orcid.org/0000-0001-5564-8750
Haoyu ChenJoint Shantou International Eye Centre of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China. drchenhaoyu@gmail.com.ORCID http://orcid.org/0000-0003-0676-4610

Funding

Guangdong Natural Science Foundation 2022A1515011396Science and Technology Planning Project of Guangdong Province of China 180917144960530Shantou Science and Technology Project 190917085269835Shantou University Scientific Research Initiation Grant NTF20021
6 · The paper itself

Abstract

purposeThis study aims to introduce the coefficient of spatial variance of choroidal thickness to describe the choroidal variation and investigate its associated factors in healthy eyes.

methodsThis retrospective cross-sectional study included 1031 eyes from 1031 subjects who received a swept-source optical coherence tomography examination. The mean choroidal thickness in the macular 6 × 6 mm region and 900 subregions of 0.2 × 0.2 mm were computed using the embedded algorithm. Before analysis, potential segmentation and magnification errors were corrected. The coefficient of spatial variance was defined as the standard deviation divided by the mean (multiplied by 100%) of the choroidal thicknesses across 900 grids. Potential factors associated with the coefficient of spatial variance were assessed using multiple linear regression.

resultsThe mean choroidal thickness of the entire 6 × 6 mm macular region was 204.50 ± 72.88 μm. The mean coefficient of spatial variance was 26.58 ± 8.24%, ranging from 11.00 to 61.58%. Statistical analysis revealed that the means choroidal thickness (β = - 0.08, R

conclusionOur study first incorporated the coefficient of spatial variance to represent the spatial variation of the choroidal thickness and observed that the greater thinning of the choroid is correlated with a more pronounced spatial variation.

Indexed as

ChoroidTomography, Optical CoherenceAdultAgedCross-Sectional StudiesFemaleHealthy VolunteersHumansMaleMiddle AgedRetrospective StudiesYoung AdultChoroidal thicknessCoefficient of spatial varianceHealthy eyesSwept-source optical coherence tomography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.