Evidence map›Paper›PMID 38972002›Full record

ArticleAllergy2024

Human nasal epithelial cells express IL-5Rα but not the co-receptor CSF2RB and do not signal to IL-5.

Aaqib Sohail, Laura Cho, Jonathan Hacker, Regan W Bergmark, Stella E Lee, Alice Maxfield, Rachel E Roditi, Daniel F Dwyer, Kathleen M Buchheit, Tanya M Laidlaw

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Allergy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Clinical and mechanistic advancements in aspirin exacerbated respiratory disease.The Journal of allergy and clinical immunology · 2025
    Review
  4. New insights into the mechanisms of aspirin-exacerbated respiratory disease.Current opinion in allergy and clinical immunology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aaqib SohailDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5917-7316
Laura ChoDivision of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Jonathan HackerDivision of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Regan W BergmarkDepartment of Surgery, Division of Otolaryngology-Head & Neck Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Stella E LeeDepartment of Surgery, Division of Otolaryngology-Head & Neck Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Alice MaxfieldDepartment of Surgery, Division of Otolaryngology-Head & Neck Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Rachel E RoditiDepartment of Surgery, Division of Otolaryngology-Head & Neck Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Daniel F DwyerDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Kathleen M BuchheitDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Tanya M LaidlawDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA.

Funding

Therapeutic Control of Aspirin-Exacerbated Respiratory DiseaseU19AI095219 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Maria Gutierrez-Arcelus · 2011 to 2026
$29.1M
The Role of IL-5 and Local Nasal Polyp Immunoglobulin Production in Aspirin-Exacerbated Respiratory DiseaseK23AI139352 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI BUCHHEIT, KATHLEEN MARY · 2019 to 2023
$1.0M
Patient-Oriented Research Mentorship and Training in Upper Airway Allergic and Inflammatory DiseasesK24AI180296 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Tanya Maria Laidlaw · 2024 to 2026
$522k
NIAID NIH HHS K23 AI139352NIAID NIH HHS K24 AI180296NIAID NIH HHS U19 AI095219
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID38972002
PMCPMC12487116

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.