Evidence map›Paper›PMID 38971933›Full record

ArticleInsights into imaging2024

Deep learning CT reconstruction improves liver metastases detection.

Achraf Kanan, Bruno Pereira, Constance Hordonneau, Lucie Cassagnes, Eléonore Pouget, Léon Appolinaire Tianhoun, Benoît Chauveau, Benoît Magnin

Abstract read
In one paragraph

Article in Insights into imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Achraf KananDepartment of Radiology, Estaing Hospital, Clermont University Hospital, Clermont-Ferrand, France.
Bruno PereiraDepartment of Biostatistics, DRCI, Clermont University Hospital, Clermont-Ferrand, France.
Constance HordonneauDepartment of Radiology, Estaing Hospital, Clermont University Hospital, Clermont-Ferrand, France.
Lucie CassagnesInstitut Pascal, UMR 6602 CNRS, Université Clermont Auvergne, Clermont-Ferrand, France.
Eléonore PougetDepartment of Radiology, Estaing Hospital, Clermont University Hospital, Clermont-Ferrand, France.
Léon Appolinaire TianhounDepartment of Radiology, Estaing Hospital, Clermont University Hospital, Clermont-Ferrand, France.
Benoît ChauveauDepartment of Radiology, Estaing Hospital, Clermont University Hospital, Clermont-Ferrand, France.
Benoît MagninDepartment of Radiology, Estaing Hospital, Clermont University Hospital, Clermont-Ferrand, France. bmagnin@chu-clermontferrand.fr.ORCID http://orcid.org/0000-0002-4246-5688

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDetection of liver metastases is crucial for guiding oncological management. Computed tomography through iterative reconstructions is widely used in this indication but has certain limitations. Deep learning image reconstructions (DLIR) use deep neural networks to achieve a significant noise reduction compared to iterative reconstructions. While reports have demonstrated improvements in image quality, their impact on liver metastases detection remains unclear. Our main objective was to determine whether DLIR affects the number of detected liver metastasis. Our secondary objective was to compare metastases conspicuity between the two reconstruction methods.

methodsCT images of 121 patients with liver metastases were reconstructed using a 50% adaptive statistical iterative reconstruction (50%-ASiR-V), and three levels of DLIR (DLIR-low, DLIR-medium, and DLIR-high). For each reconstruction, two double-blinded radiologists counted up to a maximum of ten metastases. Visibility and contour definitions were also assessed. Comparisons between methods for continuous parameters were performed using mixed models.

resultsA higher number of metastases was detected by one reader with DLIR-high: 7 (2-10) (median (Q₁-Q₃); total 733) versus 5 (2-10), respectively for DLIR-medium, DLIR-low, and ASiR-V (p < 0.001). Ten patents were detected with more metastases with DLIR-high simultaneously by both readers and a third reader for confirmation. Metastases visibility and contour definition were better with DLIR than ASiR-V.

conclusionDLIR-high enhanced the detection and visibility of liver metastases compared to ASiR-V, and also increased the number of liver metastases detected. CRITICAL RELEVANCE STATEMENT: Deep learning-based reconstruction at high strength allowed an increase in liver metastases detection compared to hybrid iterative reconstruction and can be used in clinical oncology imaging to help overcome the limitations of CT. KEY POINTS: Detection of liver metastases is crucial but limited with standard CT reconstructions. More liver metastases were detected with deep-learning CT reconstruction compared to iterative reconstruction. Deep learning reconstructions are suitable for hepatic metastases staging and follow-up.

Indexed as

Artificial intelligenceComputed tomographyDeep learningImage reconstructionLiver neoplasm

Identifiers

PMID38971933
PMCPMC11227486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.