Evidence map›Paper›PMID 38971909›Full record

ArticlePediatric surgery international2024

Urological outcomes in adult females born with anorectal malformation or Hirschsprung disease.

Lea A Wehrli, Kelly T Harris, Dan T Wood, Duncan T Wilcox, Emily H Cooper, Jared M Rieck, Elisha McGuire, Jill Ketzer, Luis De La Torre, Alberto Peña and 1 more

Abstract read
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In one paragraph

Article in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lea A WehrliInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, USA.
Kelly T HarrisInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, USA.
Dan T WoodInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, USA.
Duncan T WilcoxInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, USA.
Emily H CooperResearch in Outcomes for Children's Surgery, Center for Children's Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, USA.
Jared M RieckResearch in Outcomes for Children's Surgery, Center for Children's Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, USA.
Elisha McGuireInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, USA.
Jill KetzerInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, USA.
Luis De La TorreInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, USA.
Alberto PeñaInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, USA.
Andrea BischoffInternational Center for Colorectal and Urogenital Care, Children's Hospital Colorado, Aurora, USA. andrea.bischoff@childrenscolorado.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWomen born with anorectal malformation (ARM) or Hirschsprung disease (HD) may have impaired urologic function resulting in sequelae in adulthood. This study assessed and compared self-reported urinary outcomes in adult females born with ARM or HD to a reference population.

methodsThis was an IRB approved, cross-sectional study of female-born patients with ARM or HD, who completed surveys between November 2021 and August 2022. Female patients between the ages of 18 and 80 years were included. Lower Urinary Tract Symptom Questionnaires were administered through REDCap and the responses were compared to a reference population using Chi-squared or Fisher's exact tests.

resultsSixty-six born female patients answered the questionnaires, two of them identified as non-binary. The response rate was 76%. Median age was 31.6 years. The majority were born with cloaca (56.3%), followed by other type of ARMs (28.1%), complex malformation (9.4%), and HD (6.3%). A history of bladder reconstruction was present for 26.6%. Catheterization through a channel or native urethra was present in 18.8%. Two had ureterostomies and were excluded from the analysis. Seven had chronic kidney disease or end-stage renal disease, three with a history of kidney transplantation. Patients with cloaca had significantly higher rates of urinary incontinence, urinary tract infection, and social problems due to impaired urological functioning, when compared to an age-matched reference population (Table 3).

conclusionThis study emphasizes the need for a multi-disciplinary team that includes urology and nephrology following patients with ARM long term, especially within the subgroup of cloaca. LEVEL OF EVIDENCE: III.

Indexed as

Anorectal MalformationsHirschsprung DiseaseAdolescentAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansLower Urinary Tract SymptomsMiddle AgedSurveys and QuestionnairesYoung AdultAnorectal malformationCloacaHirschsprung diseaseUrinary functionUrinary incontinenceUrological outcome

Identifiers

PMID38971909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.