Evidence map›Paper›PMID 38971787›Full record

ArticleMicrobial cell factories2024

Mapping a sustainable approach: biosynthesis of lactobacilli-silver nanocomposites using whey-based medium for antimicrobial and bioactivity applications.

E B El Fadly, A S Salah, B Abdella, A Al Ali, H AlShmrany, A M ElBaz, N S Abdelatty, E F Khamis, O F Maagouz, M A Salamah and 3 more

Abstract read
In one paragraph

Article in Microbial cell factories, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

E B El FadlyDepartment of Dairy Sciences, Faculty of Agriculture, Kafrelsheikh University, Kafrelsheikh, Egypt. enasali.2006@gmail.com.ORCID http://orcid.org/0000-0002-3406-7284
A S SalahDepartment of Aquaculture, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.ORCID http://orcid.org/0000-0002-8063-2627
B AbdellaFaculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.ORCID http://orcid.org/0000-0001-5237-263X
A Al AliDepartment of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, University of Bisha, 255, Al Nakhil, 57714, Bisha, Saudi Arabia.ORCID http://orcid.org/0000-0002-4189-4800
H AlShmranyDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince, Sattam Bin Abdulaziz University, 11942, Alkharj, Saudi Arabia.ORCID http://orcid.org/0009-0000-3024-8494
A M ElBazDairy Microbiology Research Department, Agriculture Research Center, Animal Production Research Institute, Giza, 12611, Egypt.ORCID http://orcid.org/0009-0009-1345-526X
N S AbdelattyDepartment of Dairy Sciences, Faculty of Agriculture, Kafrelsheikh University, Kafrelsheikh, Egypt.ORCID http://orcid.org/0009-0006-2118-1631
E F KhamisDairy Chemistry Research Department, Agriculture Research Center, Animal Production Research Institute, Giza, 12611, Egypt.ORCID http://orcid.org/0009-0003-6016-7654
O F MaagouzDairy Chemistry Research Department, Agriculture Research Center, Animal Production Research Institute, Giza, 12611, Egypt.ORCID http://orcid.org/0000-0002-2859-6868
M A SalamahAgricultural Research Center, Food Technology Research Institute, Giza, 12611, Egypt.ORCID http://orcid.org/0000-0003-3025-2279
M N SalehAgricultural Research Center, Food Technology Research Institute, Giza, 12611, Egypt.ORCID http://orcid.org/0000-0003-1135-0383
H K SakrAgricultural Research Center, Food Technology Research Institute, Giza, 12611, Egypt.ORCID http://orcid.org/0000-0002-1299-3623
M A El-KemaryInstitute of Nanoscience and Nanotechnology, Kafrelsheikh University, Kafrelsheikh, Egypt. elkemary@nano.kfs.edu.eg.ORCID http://orcid.org/0000-0003-0679-1715

Funding

Prince Sattam bin Abdulaziz University PSAU/2024/R/1445The Academy of Scientific Research and Technology 33/2018
6 · The paper itself

Abstract

This study explores a sustainable approach for synthesizing silver nanocomposites (AgNCs) with enhanced antimicrobial and bioactivity using safe Lactobacillus strains and a whey-based medium (WBM). WBM effectively supported the growth of Lactobacillus delbrueckii and Lactobacillus acidophilus, triggering a stress response that led to AgNCs formation. The synthesized AgNCs were characterized using advanced spectroscopic and imaging techniques such as UV‒visible, Fourier transform infrared (FT-IR) spectroscopy, transmission electron (TEM), and scanning electron microscopy with energy dispersive X-ray analysis (SEM-Edx). Lb acidophilus-synthesized AgNCs in WBM (had DLS size average 817.2-974.3 ± PDI = 0.441 nm with an average of metal core size 13.32 ± 3.55 nm) exhibited significant antimicrobial activity against a broad spectrum of pathogens, including bacteria such as Escherichia coli (16.47 ± 2.19 nm), Bacillus cereus (15.31 ± 0.43 nm), Clostridium perfringens (25.95 ± 0.03 mm), Enterococcus faecalis (32.34 ± 0.07 mm), Listeria monocytogenes (23.33 ± 0.05 mm), methicillin-resistant Staphylococcus aureus (MRSA) (13.20 ± 1.76 mm), and filamentous fungi such as Aspergillus brasiliensis (33.46 ± 0.01 mm). In addition, Lb acidophilus-synthesized AgNCs in WBM exhibit remarkable free radical scavenging abilities, suggesting their potential as bioavailable antioxidants. These findings highlight the dual functionality of these biogenic AgNCs, making them promising candidates for applications in both medicine and nutrition.

Indexed as

Microbial Sensitivity TestsNanocompositesSilverWheyAnti-Bacterial AgentsAnti-Infective AgentsLactobacillusLactobacillus acidophilusMetal NanoparticlesSpectroscopy, Fourier Transform InfraredAnti-Bacterial AgentsAnti-Infective AgentsSilverantimicrobial Activityantioxidant activitylactobacillimultidrug resistant bacteriaSilver nanocomposites biosynthesisSpore-formerssustainable whey- based mediumSynergism

Identifiers

PMID38971787
PMCPMC11227706

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.