Evidence map›Paper›PMID 38971766›Full record

ArticleStem cell research & therapy2024

Distraction force promotes the osteogenic differentiation of Gli1

Mengying Jin, Yang An, Zheng Wang, Guanhuier Wang, Zhiyu Lin, Pengbing Ding, Enhang Lu, Zhenmin Zhao, Hongsen Bi

Abstract read
In one paragraph

Article in Stem cell research & therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Mechanical control in dental and jaw morphogenesis and remodeling.International journal of oral science · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. [Advances in the Study of Calvarial Stem Cells].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mengying Jin *Department of Plastic Surgery, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, China.
Yang An *Department of Plastic Surgery, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, China.
Zheng WangDepartment of Plastic Surgery, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, China.
Guanhuier WangDepartment of Plastic Surgery, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, China.
Zhiyu LinDepartment of Plastic Surgery, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, China.
Pengbing DingDepartment of Plastic Surgery, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, China.
Enhang LuDepartment of Plastic Surgery, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, China.
Zhenmin ZhaoDepartment of Plastic Surgery, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, China. zzmbysy@sina.com.
Hongsen BiDepartment of Plastic Surgery, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, China. bihongsen@bjmu.edu.cn.

Funding

Innovative Research Group Project of the National Natural Science Foundation of China No. 81571925
6 · The paper itself

Abstract

backgroundTrans-sutural distraction osteogenesis (TSDO) involves the application of distraction force to facial sutures to stimulate osteogenesis. Gli1

methods4-week-old Gli1ER/Td and C57BL/6 mice were used to establish a TSDO model to explore osteogenesis of zygomaticomaxillary sutures. A Gli1

resultsDistraction force promoted bone remodeling during TSDO. Fluorescence and two-photon scanning images revealed the distribution of Gli1

conclusionsOur study indicates that the primary cilia of Gli1

Indexed as

Cell DifferentiationCiliaCranial SuturesHedgehog ProteinsOsteogenesisSignal TransductionZinc Finger Protein GLI1AnimalsCell ProliferationMiceMice, Inbred C57BLOsteogenesis, DistractionGli1 protein, mouseHedgehog ProteinsZinc Finger Protein GLI1Gli1+ cellsHedgehog signalingPrimary ciliaTrans-sutural distraction osteogenesis

Identifiers

PMID38971766
PMCPMC11227703

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.