ArticleAmerican journal of ophthalmology2024
Impact of Social Vulnerability Index on the Development of Severe Visual Impairment or Blindness From Glaucoma.
Article in American journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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Who cites it
9 citing papers in PubMed.
- Primary Open-Angle Glaucoma among Black and Latinx Populations: Exploring Racial Disparities in the United States.Journal of racial and ethnic health disparities · 2026Review
- Blindness and prognostic factors after trabeculectomy with mitomycin C in patients with open-angle glaucoma with long-term follow-up.Acta ophthalmologica · 2026Article
- Care-Related Quality of Life of Caregivers for Patients With Low Vision and Blindness: A Cross-Sectional Study.Journal of ophthalmology · 2026Article
- Improved Estimation of Rates of Glaucoma Progression Using Spatial Two-Fold Linear Mixed Models.Journal of statistical theory and applications : JSTA · 2026Article
- Inefficacy of Longitudinal Cup-to-Disc Ratio Measurements in Identifying Glaucoma Progression.American journal of ophthalmology · 2025Article
- Association Between Sociodemographic Risk Factors and No-Show Propensity in a Glaucoma Population Before and During COVID-19 Pandemic.Journal of glaucoma · 2025Article
- Association Between Greater Social Vulnerability and Delayed Glaucoma Surgery.American journal of ophthalmology · 2024Article
- Loss to Follow-up and Risk of Incident Blindness among Patients with Glaucoma in the IRIS® Registry.Ophthalmology. GlaucomaArticle
- Impact of Social Vulnerability Index and Distance to Tertiary Ocular Emergency Department in Patients Presenting with Open Globe Injury.Ophthalmology scienceArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
purposeTo evaluate whether geocoded social risk factor data predict the development of severe visual impairment or blindness due to glaucoma during follow-up using a large electronic health record (EHR) database.
designCohort study.
methodsPatients diagnosed with open-angle glaucoma (OAG) at a tertiary care institution. All eyes had glaucomatous visual field defects at baseline. Sociodemographic and ocular data were extracted from the EHR, including age, gender, self-reported race and ethnicity, insurance status, OAG type, prior glaucoma laser or surgery, baseline disease severity using Hodapp-Anderson-Parrish criteria, mean intraocular pressure (IOP) during follow-up, and central corneal thickness. Social vulnerability index (SVIndex) data at the census tract level were obtained using geocoded patient residences. Mixed-effects Cox proportional hazard models were completed to assess for the development of severe visual impairment or blindness during follow-up, defined as BCVA ≤ 20/200 at least at the last two clinic visits or standard automated perimetry (SAP) mean deviation (MD) ≤ -22dB confirmed on two tests.
resultsA total of 4,046 eyes from 2,826 patients met inclusion criteria and were followed for an average of 4.3 ± 2.2 years. Severe visual impairment or blindness developed in 79 eyes (2.0%) from 76 patients (2.7%) after an average of 3.4 ± 1.8 years, leading to an incidence rate of severe visual impairment or blindness of 0.5% per year. Older age (adjusted hazards ratio [HR] 1.36 per decade, P = .007), residence in areas with higher SVIndex (HR 1.56 per 25% increase, P < .001), higher IOP during follow-up (HR 3.01 per 5 mmHg increase, P < .001), and moderate or severe glaucoma at baseline (HR 7.31 and 26.87, P < .001) were risk factors for developing severe visual impairment or blindness. Concordance index of the model was 0.88. Socioeconomic, minority status/language, and housing type/transportation SVIndex themes were key contributors to developing severe visual impairment or blindness.
conclusionsRisk factors for developing glaucoma-related severe visual impairment or blindness included older age, elevated IOP during follow-up, moderate or severe disease at baseline, and residence in areas associated with greater social vulnerability. In addition to ocular risk factors, geocoded EHR data regarding social risk factors could help identify patients at high risk of developing glaucoma-related visual impairment.
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