Evidence map›Paper›PMID 38970517›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2024

Association of whole blood copper, zinc, calcium, magnesium, and iron with non-alcoholic fatty liver disease in overweight and obese children.

Zhihang Huang, Miyang Luo, Wen Dai, Zhenzhen Yao, Sisi Ouyang, Ning'an Xu, Haixiang Zhou, Xiongwei Li, Yan Zhong, Jiayou Luo

Abstract read
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhihang HuangDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410013. 226912056@csu.edu.cn.
Miyang LuoDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410013.
Wen DaiDepartment of Maternal and Children Care, Xiangya School of Public Health, Central South University, Changsha 410013.
Zhenzhen YaoDepartment of Maternal and Children Care, Xiangya School of Public Health, Central South University, Changsha 410013.
Sisi OuyangDepartment of Maternal and Children Care, Xiangya School of Public Health, Central South University, Changsha 410013.
Ning'an XuDepartment of Children Care, Hunan Children's Hospital, Changsha 410007.
Haixiang ZhouCenter for Disease Control and Prevention of Ningxiang, Changsha 410600, China.
Xiongwei LiCenter for Disease Control and Prevention of Ningxiang, Changsha 410600, China.
Yan ZhongDepartment of Children Care, Hunan Children's Hospital, Changsha 410007. zhongyan@163.com.
Jiayou LuoDepartment of Maternal and Children Care, Xiangya School of Public Health, Central South University, Changsha 410013. jiayouluo@126.com.

Funding

the Natural Science Foundation of Hunan Province 2021JJ30901
6 · The paper itself

Abstract

objectivesNon-alcoholic fatty liver disease (NAFLD) is a common metabolic disorder in overweight and obese children, and its etiology and pathogenesis remain unclear, lacking effective preventive and therapeutic measures. This study aims to explore the association between whole blood copper, zinc, calcium, magnesium and iron levels and NAFLD in overweight and obese children aged 6 to 17 years, providing a scientific basis for the prevention and intervention of early NAFLD in overweight and obese children.

methodsA cross-sectional study design was used to collect relevant data from overweight and obese children who visited the Hunan Children's Hospital from January 2019 to December 2021 through questionnaire surveys. Fasting blood samples were collected from the subjects, and various indicators such as blood glucose, blood lipid, and mineral elements were detected. All children were divided into an overweight group (

resultsA total of 602 subjects were included, of whom 73.6% were male, with a median age of 10 (9, 11) years, and a body mass index (BMI) of 24.9 (22.7, 27.4) kg/m

conclusionsHigh iron level increases the risk of NAFLD (more likely NAFL) in overweight and obese children, while copper, zinc, calcium, magnesium, and other elements are not associated with the risk of NAFLD in overweight and obese children.

Indexed as

CalciumCopperIronMagnesiumNon-alcoholic Fatty Liver DiseaseOverweightZincAdolescentChildCross-Sectional StudiesFemaleHumansMalePediatric ObesityCalciumCopperIronMagnesiumZincchildrenmineralsnon-alcoholic fatty liver diseaseoverweight and obese

Identifiers

PMID38970517
PMCPMC11208402

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.