Evidence map›Paper›PMID 38970216›Full record

Trial reportBrain and behavior2024

Effects of repetitive transcranial magnetic stimulation of the right inferior parietal lobe on the body image perception in anorexia nervosa: A pilot randomized controlled study.

Nathalie Chastan, Najate Achamrah, Olivier Etard, Clément Nathou, Marie-Astrid Piquet, Sébastien Guillaume, Jérôme Attal, André Gillibert, Pierre Dechelotte, Olivier Guillin and 1 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Review
  7. rTMS Therapy for Eating Disorders: Scoping Review on Efficacy, Safety, Stimulation Parameters and Study Subjects.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nathalie ChastanDepartment of Neurophysiology, Normandie University, UNIROUEN, Rouen University Hospital, Rouen, France.
Najate AchamrahDepartment of Nutrition, Normandie University, UNIROUEN, INSERM UMR1073, Rouen University Hospital, Rouen, France.
Olivier EtardDepartment of Neurophysiology, Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU Caen, Caen, France.
Clément NathouDepartment of Neurophysiology, Normandie University, UNICAEN, INSERM, COMETE, CYCERON, CHU Caen, Caen, France.
Marie-Astrid PiquetDepartment of Nutrition, CHU Caen, Caen, France.
Sébastien GuillaumeDepartment of Emergency Psychiatry and Acute Care, Lapeyronie Hospital, CHU Montpellier, Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.ORCID 0000-0002-6769-9982
Jérôme AttalDepartment of Emergency Psychiatry and Acute Care, Lapeyronie Hospital, CHU Montpellier, Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
André GillibertDepartment of Biostatistics, CHU Rouen, Rouen, France.
Pierre DechelotteDepartment of Nutrition, Normandie University, UNIROUEN, INSERM UMR1073, Rouen University Hospital, Rouen, France.
Olivier GuillinDepartment of Psychiatry, Normandie University, UNIROUEN, Rouen University Hospital, Rouen, France.
Marie-Laure WelterDepartment of Neurophysiology, Normandie University, UNIROUEN, Rouen University Hospital, Rouen, France.ORCID 0000-0003-1423-5620

Funding

French Ministry of Health
6 · The paper itself

Abstract

introductionRestrictive anorexia nervosa (AN) is associated with distorted perception of body shape, previously linked to hypoactivity and reduced excitability of the right inferior parietal lobe (rIPL). Here, we investigated the impact of high-frequency repetitive transcranial magnetic stimulation (HF rTMS) of the rIPL on body shape perception in patients with AN.

methodsSeventeen patients with AN (median [Q1_Q3] age, 35 [27_39] years; disease duration, 12 [6_18] years) were randomly assigned to receive real or sham HF (10 Hz) rTMS of the rIPL over a period of 2 weeks, comprising 10 sessions. The primary outcome measure was the Body Shape Questionnaire (BSQ). Secondary outcomes included eating disorder symptoms, body mass index, mood, anxiety, and safety. Data collection were done at baseline, post-rTMS, and at 2 weeks and 3 months post-rTMS.

resultsFollowing both real and sham rTMS of the rIPL, no significant differences were observed in body shape perception or other parameters. Both real and sham rTMS interventions were deemed safe and well tolerated. Notably, serious adverse events were associated with the underlying eating and mood disorders, resulting in hospitalization for undernutrition (five patients) or suicidal attempts (two patients).

conclusionThis pilot study does not support the use of rTMS of the rIPL as an effective method for improving body shape perception in individuals with the restrictive form of AN. Further research is warranted to comprehensively explore both the clinical and neurophysiological effects of HF rTMS in this population.

Indexed as

Anorexia NervosaBody ImageParietal LobeTranscranial Magnetic StimulationAdultFemaleHumansMalePilot ProjectsTreatment Outcomeanorexia nervosabody imagerepetitive transcranial magnetic stimulationright inferior parietal lobe

Identifiers

PMID38970216
PMCPMC11226536

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.