Evidence map›Paper›PMID 38970118›Full record

SynthesisJournal of translational medicine2024

Effects of magnesium supplementation on muscle soreness in different type of physical activities: a systematic review.

Maria Grazia Tarsitano, Federico Quinzi, Katia Folino, Francesca Greco, Francesco Pio Oranges, Claudia Cerulli, Gian Pietro Emerenziani

Registry-linked trialAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07662954 (Effects of Magnesium Supplementation and Spinning Training on Cardiac Function, Oxidative Stress, Inflammation, and Aerobic Capacity), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07662954 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Effects of Magnesium Supplementation and Spinning Training on Cardiac Function, Oxidative Stress, Inflammation, and Aerobic Capacity

TypeinterventionalSponsorKaramanoğlu Mehmetbey UniversityRan2026 to 2026Enrolled48ConditionsOxidative Stress, Inflammation, Physical Fitness, EchocardiographyArmsSpinning Training, Magnesium Supplementation
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria Grazia TarsitanoDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, 88100, Catanzaro, CZ, Italy. mariagrazia.tarsitano@unicz.it.
Federico QuinziDepartment of Experimental and Clinical Medicine, University "Magna Græcia" of Catanzaro, Catanzaro, CZ, Italy.
Katia FolinoDepartment of Experimental and Clinical Medicine, University "Magna Græcia" of Catanzaro, Catanzaro, CZ, Italy.
Francesca GrecoDepartment of Movement, Human and Health Sciences, University "Foro Italico" of Rome, RM, Italy.
Francesco Pio OrangesDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, 88100, Catanzaro, CZ, Italy.
Claudia CerulliDepartment of Movement, Human and Health Sciences, University "Foro Italico" of Rome, RM, Italy.
Gian Pietro EmerenzianiDepartment of Experimental and Clinical Medicine, University "Magna Græcia" of Catanzaro, Catanzaro, CZ, Italy.

Funding

Italian Ministry of Education and University 2017FJSM9S
6 · The paper itself

Abstract

backgroundMagnesium is a micronutrient and an intracellular cation responsible for different biochemical reactions involved in energy production and storage, control of neuronal and vasomotor activity, cardiac excitability, and muscle contraction. Magnesium deficiency may result in impaired physical performance. Moreover, magnesium plays an important role on delayed onset muscle soreness after training. Thus, physically active individuals and sport specialists have to pay attention to magnesium supplementation (MgS). However, the type, timing and dosage of magnesium intake are not well elucidated yet. Hence, we aimed to systematically review the literature regarding the effects of MgS on muscle soreness in physically active individuals. We focused exclusively on MgS, excluding those studies in which magnesium was administered together with other substances.

methodsThree electronic databases and literature sources (PUBMED, SCOPUS and Web of Sciences-Core Collection) were searched, in accordance with PRISMA guidelines. After the database search, 1254 articles were identified, and after excluding duplicates, 960 articles remained. Among these, 955 were excluded following the title and abstract screening. The remaining 5 articles were screened in full text and 4 study met the eligibility criteria.

resultsThese studies showed that MgS reduced muscle soreness, improved performance, recovery and induced a protective effect on muscle damage.

conclusionTo reach these positive effects, individuals engaged in intense exercise should have a Mg requirement 10-20% higher than sedentary people, to be taken in capsules and 2 h before training. Moreover, it is suggested to maintain magnesium levels in the recommended range during the off-season. SYSTEMATIC REVIEW REGISTRATION: PROSPERO registration number: CRD42024501822.

Indexed as

Dietary SupplementsExerciseMagnesiumMyalgiaHumansMaleMagnesiumDosageFitnessMgMicronutrientPhysical activityPhysical performance

Identifiers

PMID38970118
PMCPMC11227245

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.