Evidence map›Paper›PMID 38970085›Full record

ArticleBMC research notes2024

Neurobehavioral, neurotransmitter and redox modifications in Nauphoeta cinerea under mixed heavy metal (silver and mercury) exposure.

Olawande C Olagoke, Opeyemi B Ogunsuyi, Famutimi E Mayokun, João B T Rocha, Ganiyu Oboh

Abstract read
In one paragraph

Article in BMC research notes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olawande C OlagokeDivision of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. olawande.olagoke@kiu.ac.ug.
Opeyemi B OgunsuyiDepartment of Biomedical Technology, Federal University of Technology, P.M.B. 704, Akure, Nigeria.
Famutimi E MayokunDepartment of Biomedical Technology, Federal University of Technology, P.M.B. 704, Akure, Nigeria.
João B T RochaPrograma de Pos-graduacao em Bioquimica Toxicologica, Departamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas (CCNE), Universidade Federal de Santa Maria, Santa Maria, RS, 97105-900, Brazil.
Ganiyu ObohDrosophila Research Lab, Functional Foods and Nutraceuticals Unit, Federal University of Technology, P.M.B. 704, Akure, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heavy metals are encountered in nature, and are used in several human endeavors, including in dental fillings. It is well known that the safety of metals depends on their chemical form, as well as the dose and route through which biological systems are exposed to them. Here, we used the Nauphoeta cinerea model to examine the mechanism by which salts of the heavy metals used in dental fillings - silver and mercury - exert their neurotoxicity. Nymphs exposed to heavy metals presented with reduced motor and exploratory abilities as they spent more time immobile, especially in the periphery of a novel object, and covered less distance compared with control nymphs. Exposure to AgNO

Indexed as

Oxidation-ReductionOxidative StressAcetylcholinesteraseAnimalsBehavior, AnimalMercuric ChlorideMercuryMonoamine OxidaseNeurotransmitter AgentsNymphReactive Oxygen SpeciesSilverSilver NitrateAcetylcholinesteraseMercuric ChlorideMercuryMonoamine OxidaseNeurotransmitter AgentsReactive Oxygen SpeciesSilverSilver Nitrate3RsAmalgam banMercury toxicityNeurotoxicitySilver toxicity

Identifiers

PMID38970085
PMCPMC11227235

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.