Evidence map›Paper›PMID 38969825›Full record

ReviewJournal of perinatology : official journal of the California Perinatal Association2024

Advocating for the inclusion of kidney health outcomes in neonatal research: best practice recommendations by the Neonatal Kidney Collaborative.

Kimberly J Reidy, Ronnie Guillet, David T Selewski, Marissa Defreitas, Sadie Stone, Michelle C Starr, Matthew W Harer, Namrata Todurkar, Kim T Vuong, Semsa Gogcu and 3 more

Abstract readReview
In one paragraph

Review in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Impact of maternal health on neonatal and long-term kidney outcomes.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Kidney care at NICU discharge and follow-up recommendations for preterm infants<34 weeks.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  6. Article
  7. What's next in neonatal acute kidney injury? Discussion from the pediatric academic society neonatal nephrology focus group.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kimberly J Reidy *Division of Nephrology, Department of Pediatrics, Children's Hospital at Montefiore/Albert Einstein College of Medicine, Bronx, NY, 10467, USA.ORCID 0000-0002-7680-457X
Ronnie Guillet *Division of Neonatology, Golisano Children's Hospital, University of Rochester, Rochester, NY, USA.ORCID 0000-0003-4394-344X
David T SelewskiDivision of Nephrology, Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0003-0358-0760
Marissa DefreitasDivision of Nephrology, Department of Pediatrics, University of Miami/Holtz Children's Hospital, Miami, FL, USA.
Sadie StoneDepartment of Pharmacy, Children's of Alabama, Birmingham, AL, UK.ORCID 0000-0003-2507-3903
Michelle C StarrDivision of Pediatric Nephrology, Division of Child Health Service Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.ORCID 0000-0001-9412-8950
Matthew W HarerDivision of Neonatology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.ORCID 0000-0001-5493-3269
Namrata TodurkarDivision of Neonatal Perinatal Medicine, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Kim T VuongDivision of Pediatric Nephrology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0001-9177-819X
Semsa GogcuSection of Neonatal-Perinatal Medicine, Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC, USA.ORCID 0000-0002-0429-9404
David AskenaziDivision of Nephrology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, UK.
Trent E TippleSection of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.ORCID 0000-0002-5156-4282
Jennifer R CharltonDivision of Nephrology, Department of Pediatrics, University of Virginia, Box 800386, Charlottesville, VA, 22903, USA. jrc6n@virginia.edu.ORCID 0000-0002-2225-535X

Funding

Investigating the effect of dysregulated vitamin D metabolism on kidney development following preterm birthR01DK136989 · NIDDK · UNIVERSITY OF VIRGINIA · PI Jennifer R Charlton, Kimberly Jean Reidy · 2024 to 2026
$2.1M
Improving the prediction of bronchopulmonary dysplasia by identifying kidney-based risk factorsK23HL168362 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Michelle C Starr · 2024 to 2026
$547k
NHLBI NIH HHS K23 HL168362NIDDK NIH HHS R01 DK136989U.S. Department of Health &amp; Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes &amp; Digestive &amp; Kidney Diseases) R01DK136989
6 · The paper itself

Abstract

Acute kidney injury (AKI) occurs in nearly 30% of sick neonates. Chronic kidney disease (CKD) can be detected in certain populations of sick neonates as early as 2 years. AKI is often part of a multisystem syndrome that negatively impacts developing organs resulting in short- and long-term pulmonary, neurodevelopmental, and cardiovascular morbidities. It is critical to incorporate kidney-related data into neonatal clinical trials in a uniform manner to better understand how neonatal AKI or CKD could affect an outcome of interest. Here, we provide expert opinion recommendations and rationales to support the inclusion of short- and long-term neonatal kidney outcomes using a tiered approach based on study design: (1) observational studies (prospective or retrospective) limited to data available within a center's standard practice, (2) observational studies involving prospective data collection where prespecified kidney outcomes are included in the design, (3) interventional studies with non-nephrotoxic agents, and (4) interventional studies with known nephrotoxic agents. We also provide recommendations for biospecimen collection to facilitate ancillary kidney specific research initiatives. This approach balances the costs of AKI and CKD ascertainment with knowledge gained. We advocate that kidney outcomes be included routinely in neonatal clinical study design. Consistent incorporation of kidney outcomes across studies will increase our knowledge of neonatal morbidity.

Indexed as

Acute Kidney InjuryRenal Insufficiency, ChronicBiomedical ResearchHumansInfant, NewbornNeonatologyObservational Studies as TopicPractice Guidelines as TopicResearch Design

Identifiers

PMID38969825
PMCPMC11606916

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.