ArticleJournal of the American Chemical Society2024
Palladium-Catalyzed Amination of Aryl Halides with Aqueous Ammonia and Hydroxide Base Enabled by Ligand Development.
Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Carbenylative Buchwald-Hartwig Coupling of Aryl Halides, N-Tosylhydrazones, and Anilines.Journal of the American Chemical Society · 2026Article
- Sustainable Pd-Catalyzed Aminations "on Dirty Water".Angewandte Chemie (International ed. in English) · 2026Article
- Dual-Ligand System for Mild Decarbonylative Suzuki-Miyaura Cross-Coupling of Aroyl Chlorides.ACS catalysis · 2026Article
- The Heterocycle Isostere Explorer: A Computational Tool for the Discovery of Novel Aromatic Heterocyclic Isosteres.Journal of medicinal chemistry · 2026Article
- Mechanism-Inspired Ligand Design for Efficient Copper-Catalyzed C-N Coupling of Aryl and Heteroaryl Chlorides.Journal of the American Chemical Society · 2026Article
- Photothermal Conversion Promotes Challenging SAngewandte Chemie (International ed. in English) · 2026Article
- Synthesis andOrganic letters · 2025Article
- General method for carbon-heteroatom cross-coupling reactions via semiheterogeneous red-light metallaphotocatalysis.Nature communications · 2025Article
- Recent Green and Sustainable Pd-Catalyzed Aminations.ChemSusChem · 2025Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The conversion of aryl halides to primary arylamines with a convenient and inexpensive source of ammonia has been a long-standing synthetic challenge. Aqueous ammonia would be the most convenient and least expensive form of ammonia, but such a palladium-catalyzed amination reaction with a high concentration of water faces challenges concerning catalyst stability and competing hydroxylation, and palladium-catalyzed reactions with this practical reagent are rare. Further, most reactions with ammonia to form primary amines are conducted with
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Registered trials
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