Evidence map›Paper›PMID 38968054›Full record

ReviewJournal of Huntington's disease2024

Towards Standardizing Nomenclature in Huntington's Disease Research.

Marian DiFiglia, Blair R Leavitt, Douglas Macdonald, Leslie M Thompson, Huntington’s Disease Nomenclature Working Group:

Abstract readReview
In one paragraph

Review in Journal of Huntington's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Systematic Review with Meta-Analysis of Biofluid Markers for Huntington's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marian DiFigliaDepartment of Neurology, MassGeneral Institute for Neurodegenerative Disease, Harvard Medical School, Charlestown, MA, USA.
Blair R LeavittCenter for Molecular Medicine and Therapeutics and Departments of Medical Genetics and Medicine, University of British Columbia, Vancouver, BC, Canada.
Douglas MacdonaldCHDI Management, Inc., The Company that Manages the Scientific Activities of CHDI Foundation, Inc, Los Angeles, CA, USA.
Leslie M ThompsonDepartments of Psychiatry and Human Behavior and Neurobiology and Behavior, University of California, Irvine, CA, USA.
Huntington’s Disease Nomenclature Working Group:

Funding

Understanding the mechanisms that modulate the effects of mutant Huntingtin lowering in aging Huntington's disease model miceR01NS124728 · NINDS · UNIVERSITY OF VIRGINIA · PI Scott Zeitlin · 2022 to 2026
$2.1M
6 · The paper itself

Abstract

The field of Huntington's disease research covers many different scientific disciplines, from molecular biology all the way through to clinical practice, and as our understanding of the disease has progressed over the decades, a great deal of different terminology has accrued. The field is also renowned for its collaborative spirit and use of standardized reagents, assays, datasets, models, and clinical measures, so the use of standardized terms is especially important. We have set out to determine, through a consensus exercise involving basic and clinical scientists working in the field, the most appropriate language to use across disciplines. Nominally, this article will serve as the style guide for the Journal of Huntington's Disease (JHD), the only journal devoted exclusively to HD, and we lay out the preferred and standardized terminology and nomenclature for use in JHD publications. However, we hope that this article will also serve as a useful resource to the HD research community at large and that these recommended naming conventions will be adopted widely.

Indexed as

Huntington DiseaseTerminology as TopicBiomedical ResearchHumansHTTHuntington diseasemHTTneuroanatomyneuropathologyNomenclaturepreclinical models

Identifiers

PMID38968054
PMCPMC11307060

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.