ArticleJournal of ultrasound2024
Superb microvascular imaging (SMI) and elastosonography in thyroid nodule: diagnostic value in a real-time cohort.
Article in Journal of ultrasound, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Superb microvascular imaging enhances detection of microvascularity in plantar fasciosis: a clinical correlation study.Skeletal radiology · 2026Article
- Predictors of retreatment after radiofrequency ablation of benign thyroid nodules: role of pre-treatment growth rate and viable volume.European thyroid journal · 2026Article
- The Value of a Predictive Model Based on Multimodal Ultrasound Imaging Biomarkers Combined with Clinical Features in the Diagnosis of Thyroid Nodules.Current medical imaging · 2026Article
- Evaluating the clinical impact of integrating superb microvascular imaging and shear wave elastography into TI-RADS.Journal of ultrasound · 2025Article
- Microvascular Ultrasonography Vascularity Index as a Rapid and Simplified Assessment Tool for Differentiating Graves' Disease from Destructive Thyroiditis and Managing Thyrotoxicosis.Endocrinology and metabolism (Seoul, Korea) · 2025Article
- Recent Advances in Diagnostics and Therapeutics for Paediatric Thyroid Cancer.Journal of paediatrics and child health · 2025Review
- Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn clinical practice, thyroid nodules are classified according to TI-RADS by B-mode and color-flow Doppler study. The aim of the study is to evaluate the possible added value of Superb microvascular imaging (SMI) and elastosonography in the stratification of malignancy risk of thyroid nodules.
methodsAll patients with thyroid nodules who were candidates for needle aspiration were enrolled. Experienced operators performed a standard examination with TI-RADS calculation, followed by SMI and elastosonography on the nodules. The needle aspiration outcome was used as the gold standard. Statistical analysis calculated the ROC curves of the techniques applied individually and serially.
resultsIn this prospective study, we analysed 260 nodules, found in 251 patients (mean age 58.6 yo ± 14). 11.2% were TI-RADS 1, 18.9% TI-RADS 2, 41.1% TI-RADS 3, 28.1% TI-RADS 4, and 0.8% TI-RADS 5. The SMI technique showed an AUC of 0.57 (95% CI 0.49; 0.66) while elastosonography had an AUC of 0.58 (95% CI 0.49; 0.67) when used individually. SMI together with elastosonography had AUC of 0.62 (95% CI 0.52; 0.71). TI-RADS had AUC of 0.67 (95% CI 0.59; 0.75). SMI and elastosonography applied together with TI-RADS had AUC of 0.69 (95% CI 0.61; 0.77).
conclusionIn the real-world cohort of patients, the SMI technique and elastosonography slightly increase the AUC of TI-RADS. Taken individually, SMI and elastosonography do not have a very strong AUC.
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