Evidence map›Paper›PMID 38967699›Full record

ArticleCell biology and toxicology2024

Delivery of miR-15b-5p via magnetic nanoparticle-enhanced bone marrow mesenchymal stem cell-derived extracellular vesicles mitigates diabetic osteoporosis by targeting GFAP.

Chen Xu, Zhaodong Wang, Yajun Liu, Keyou Duan, Jianzhong Guan

Abstract read
In one paragraph

Article in Cell biology and toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Role of microRNA in Diabetic Osteoporosis.Molecular biotechnology · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chen XuDepartment of Orthopedics, Bengbu Medical University Affiliated to First Hospital, Anhui Province Key Laboratory of Tissue Transplantation (Bengbu Medical College), 2600 Donghai Avenue, No. 287, Changhuai Road, Longzihu District, Bengbu, 233000, Anhui Province, China.
Zhaodong WangDepartment of Orthopedics, Bengbu Medical University Affiliated to First Hospital, Anhui Province Key Laboratory of Tissue Transplantation (Bengbu Medical College), 2600 Donghai Avenue, No. 287, Changhuai Road, Longzihu District, Bengbu, 233000, Anhui Province, China.
Yajun LiuDepartment of Orthopedics, Bengbu Medical University Affiliated to First Hospital, Anhui Province Key Laboratory of Tissue Transplantation (Bengbu Medical College), 2600 Donghai Avenue, No. 287, Changhuai Road, Longzihu District, Bengbu, 233000, Anhui Province, China.
Keyou DuanDepartment of Orthopedics, Bengbu Medical University Affiliated to First Hospital, Anhui Province Key Laboratory of Tissue Transplantation (Bengbu Medical College), 2600 Donghai Avenue, No. 287, Changhuai Road, Longzihu District, Bengbu, 233000, Anhui Province, China.
Jianzhong GuanDepartment of Orthopedics, Bengbu Medical University Affiliated to First Hospital, Anhui Province Key Laboratory of Tissue Transplantation (Bengbu Medical College), 2600 Donghai Avenue, No. 287, Changhuai Road, Longzihu District, Bengbu, 233000, Anhui Province, China. jianzhongguan2021@126.com.

Funding

Anhui Provincial Department Key Laboratory Open Subject General Project AHTT2022B002Anhui Provincial Department of Education Key Project 2022AH051493
6 · The paper itself

Abstract

Diabetic osteoporosis (DO) presents significant clinical challenges. This study aimed to investigate the potential of magnetic nanoparticle-enhanced extracellular vesicles (GMNP

Indexed as

Diabetes Mellitus, ExperimentalExtracellular VesiclesGlial Fibrillary Acidic ProteinMagnetite NanoparticlesMesenchymal Stem CellsMicroRNAsOsteoporosisAnimalsBone Marrow CellsCell LineHumansOsteoclastsRatsRats, WistarGfap protein, ratGlial Fibrillary Acidic ProteinMagnetite NanoparticlesMicroRNAsBone marrow mesenchymal stem cellDiabetic osteoporosisExtracellular vesicleGFAPMagnetic nanoparticlemiR-15b-5pOsteoclast differentiation

Identifiers

PMID38967699
PMCPMC11226493

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.