ReviewJournal of neurology2024
Fatigue in multiple sclerosis: can we measure it and can we treat it?
Review in Journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Somatosensory processing in long COVID fatigue and its relations with physiological and psychological factors.Experimental physiology · 2026Article
- The effects of Pilates training combined with whole-body vibration on balance and mobility in people with multiple sclerosis: A single-blind randomized controlled clinical trial.Turkish journal of physical medicine and rehabilitation · 2026Article
- Data-Driven Fatigue Trajectories in Multiple Sclerosis and Their Predictors.Neurology(R) neuroimmunology & neuroinflammation · 2026Article
- Fatigue and contributing factors in relapsing-remitting multiple sclerosis: a descriptive study based on the comprehensive fatigue assessment battery for multiple sclerosis (CFAB-MS).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Fatigue rather than cognitive reserve is associated with self-management in low-disability multiple sclerosis.Acta neurologica Belgica · 2026Article
- Rethinking prognosis in multiple sclerosis: a multiaxial perspective.Nature reviews. Neurology · 2026Review
- The correlation between serum markers of oxidative stress and fatigue and related factors in minimally disabled patients with relapsing-remitting multiple sclerosis.Scientific reports · 2026Article
- Assessing the reliability and validity of the Italian EQ-5D-5 L in multiple sclerosis: a cross-sectional study.Journal of patient-reported outcomes · 2026Article
- Development of a New Patient-Reported Outcome to Measure Fatigue in Patients with Multiple Sclerosis.Nursing reports (Pavia, Italy) · 2026Article
- Neurophysiological, imaging and neurobiological markers of central fatigue in multiple sclerosis.Brain communications · 2026Article
- Predicting Quality of Life in Relapsing-Remitting Multiple Sclerosis: Clinical Burden Meets Emotional Balance in Early Disease.Neurology international · 2025Article
- Differences in the Neural Substrate for Physical and Mental Quality of Life in Patients With Multiple Sclerosis.Brain and behavior · 2025Article
- Psychosocial Correlates of Fatigue in Young Adults with Multiple Sclerosis: Exploring the Roles of Resilience, Mindfulness, and Illness Perception.Healthcare (Basel, Switzerland) · 2025Article
- Clinical and paraclinical features distinguish fatigue from depression-predominant phenotypes in multiple sclerosis.Scientific reports · 2025Observational
- The Impact of Urodynamic Findings on Fatigue and Depression in People with Multiple Sclerosis.Biomedicines · 2025Article
- A qualitative comparison of healthcare practitioners' perceptions regarding fatigue as a symptom in neurological conditions: insights from a tertiary care center in Saudi Arabia.Frontiers in rehabilitation sciences · 2025Article
- Multimodal Neuroimaging and Electrophysiological Markers in Multiple Sclerosis: An Integrative Review of fMRI, EEG, and EMG Approaches : fMRI, EEG, EMG in Multiple Sclerosis.Galen medical journal · 2025Review
- EBNA-1 and VCA-p18 immunoglobulin markers link Epstein-Barr virus immune response and brain's myelin content to fatigue in a community-dwelling cohort.Brain, behavior, & immunity - health · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fatigue is a common and debilitating symptom in multiple sclerosis (MS). However, after over 100 years of inquiry its definition, measurement and understanding remains elusive. This paper describes the challenges clinicians and researchers face when assessing and treating MS patients, as well as our understanding of neural mechanisms involved in fatigue. Challenges for the future are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.