Evidence map›Paper›PMID 38967082›Full record

SynthesisCurrent medicinal chemistry2025

Immunological Activity of Vaccine Systems Containing Liposomal Nanocarriers against Protozoan-induced Diseases: A Systematic Review.

Francisco Dantas Lourenco, João Victor Lima Teixeira, Gabriel Acacio de Moura, Yasmim Mendes Rocha, Joao Pedro Viana Rodrigues, Juliana Ramos de Oliveira, Cristian Vicson Pinheiro, Larissa Deadame de Figueiredo Nicolete, Roberto Nicolete

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Veterinary sciences · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francisco Dantas LourencoHealth Science Institute, International Integration University of Afro-Brazilian Lusophony (UNILAB), Redenção - CE, Brazil.
João Victor Lima TeixeiraHealth Science Institute, International Integration University of Afro-Brazilian Lusophony (UNILAB), Redenção - CE, Brazil.
Gabriel Acacio de MouraOswaldo Cruz Foundation (FIOCRUZ CEARÁ), Eusébio - CE, Brazil.
Yasmim Mendes RochaOswaldo Cruz Foundation (FIOCRUZ CEARÁ), Eusébio - CE, Brazil.
Joao Pedro Viana RodriguesOswaldo Cruz Foundation (FIOCRUZ CEARÁ), Eusébio - CE, Brazil.
Juliana Ramos de OliveiraOswaldo Cruz Foundation (FIOCRUZ CEARÁ), Eusébio - CE, Brazil.
Cristian Vicson PinheiroOswaldo Cruz Foundation (FIOCRUZ CEARÁ), Eusébio - CE, Brazil.
Larissa Deadame de Figueiredo NicoleteHealth Science Institute, International Integration University of Afro-Brazilian Lusophony (UNILAB), Redenção - CE, Brazil.
Roberto NicoleteOswaldo Cruz Foundation (FIOCRUZ CEARÁ), Eusébio - CE, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeglected parasitic diseases constitute a broad spectrum of clinical conditions that, in the chronic phase, lack effective therapies for the target population. The utilization of vaccines based on liposomal nanocarrier systems is emerging, thereby enhancing clinical outcomes in various comorbidities. Consequently, this study aims to assess the immunological activity induced by liposomal nanocarriers against neglected parasitic diseases.

methodsFor the review, the Pubmed, Embase, and Lilacs databases were used using the descriptors vaccine, parasite, and liposome. The following inclusion criteria were adopted:

resultsA total of 226 articles were identified, from which 34 were selected for review. The primary diseases identified included Babesia bovis,

conclusionTherefore, the administration of liposomal nanovaccine systems can effectively ameliorate the clinical condition of patients by modulating their immunological profile.

Indexed as

Drug CarriersLiposomesNanoparticlesProtozoan InfectionsProtozoan VaccinesAnimalsCytokinesHumansCytokinesDrug CarriersLiposomesProtozoan VaccineschemokinescytokinesliposomenanotechnologyNeglected diseasesparasite.

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.