Evidence map›Paper›PMID 38967069›Full record

ReviewCurrent pharmaceutical design2024

Overview of Spanlastics: A Groundbreaking Elastic Medication Delivery Device with Versatile Prospects for Administration

Lalit Kumar, Ritesh Rana, Gauree Kukreti, Vikas Aggarwal, Himanshu Chaurasia, Puneet Sharma, Vuluchala Jyothiraditya

Abstract readReview
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In one paragraph

Review in Current pharmaceutical design, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lalit KumarDepartment of Pharmaceutics, GNA School of Pharmacy, GNA University, Phagwara, Punjab 144401, India.
Ritesh RanaDepartment of Pharmaceutical Sciences (Pharmaceutics), Laureate Institute of Pharmacy, Kathog-Kangra, Himachal Pradesh 176031, India.
Gauree KukretiSchool of Pharmaceutical Sciences and Technology, Sardar Bhagwan Singh University, Balawala Dehradun, Uttarakhand 248161, India.
Vikas AggarwalSenior Pharmacovigilance Specialist, Continuum India LLP, 3rd Floor, Tower F DLF Building, Chandigarh Technology Park, Chandigarh 160101, India.
Himanshu ChaurasiaDepartment of Pharmacy, Quantum School of Health Science, Quantum University, Vill. Mandawar (N.H.73), Roorkee-Dehradun Highway, Roorkee, Uttrakhand 247662, India.
Puneet SharmaDepartment of Pharmaceutical Sciences (Pharmaceutics), Himachal Institute of Pharmaceutical Education and Research (HIPER), Bela-Nadaun, District-Hamirpur, H.P. 177033, India.
Vuluchala JyothiradityaCenter for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu 602105, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When compared to the challenges associated with traditional dosage forms, medication delivery systems based on nanotechnology have been a huge boon. One such candidate for medication delivery is spanlastics, an elastic nanovesicle that can transport a diverse array of medicinal compounds. The use of spanlastics has been associated with an increase in interest in alternative administration methods. The non-ionic surfactant or surfactant blend is the main component of spanlastics. The purpose of this review was primarily to examine the potential of spanlastics as a delivery system for a variety of medication classes administered via diverse routes. Science Direct, Google Scholar, and Pubmed were utilized to search the academic literature for this review. Several studies have demonstrated that spanlastics greatly improve therapeutic effectiveness, increase medication absorption, and decrease drug toxicity. This paper provides a summary of the composition and structure of spanlastics along with their utility in the delivery of various therapeutic agents by adopting different routes. Additionally, it provides an overview of the numerous disorders that may be treated using drugs that are contained in spanlastic vesicles.

Indexed as

Drug Delivery SystemsAnimalsDrug Administration RoutesElasticityHumansNanotechnologyPharmaceutical PreparationsSurface-Active AgentsPharmaceutical PreparationsSurface-Active AgentsDrug toxicityelastic nanovesiclemedicinal compounds.nanotechnologynon-ionic surfactantspanlastics

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.