ArticleOpen forum infectious diseases2024
Recommendations for Updating Fever and Inflammation of Unknown Origin From a Modified Delphi Consensus Panel.
Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- State-of-the-Art Review: Contemporary Ambulatory Approach to Adult Fever of Unknown Origin.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Review
- Possible Gastroenterological Causes of FUO (Fever of Unknown Origin).Journal of clinical medicine · 2026Review
- Adult patients with autoinflammation of unknown origin partially phenocopy the immune presentation of Still's disease.Nature communications · 2026Article
- Pyrexia of Unknown Origin (PUO) in South Asia: A Systematic Review of Diagnostic Gaps and Management Strategies.Research square · 2026Article
- Fungal diagnostic stewardship in immunocompromised populations: a focus on molds and dimorphic fungi.Clinical microbiology reviews · 2026Review
- Clinical and Laboratory Discriminators for Tuberculosis and Lymphoma in Adults Presenting with Fever of Unknown Origin: A Prospective Cohort Study.International journal of general medicine · 2026Article
- Splenic, Nonhairy, B-Cell Lymphoma Presenting as Fever of Unknown Origin.Case reports in medicine · 2026Article
- Fever of unknown origin (FUO): a 7-year clinical experience, etiological distribution, and diagnostic approaches.BMC infectious diseases · 2025Article
- Diagnostic Value of Machine Learning Models in Inflammation of Unknown Origin.Journal of clinical medicine · 2025Article
- A scoping review on potential of novel developments in fever of unknown origin and inflammation of unknown origin: long-axial-field-of-view positron emission tomography/computed tomography and novel radiotracers.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2025Article
- Role ofJournal of clinical medicine · 2025Review
- Uncovering Sternoclavicular Arthritis, Suspected Pseudogout, in a Fever of Unknown Origin by Whole-Body MRI.Diagnostics (Basel, Switzerland) · 2025Article
- Reply to Which Role for [18F]FDG PET/CT in the "Recommendations for Updating Fever and Inflammation of Unknown Origin From a Modified Delphi Consensus Panel" by Wright et al.?Open forum infectious diseases · 2024Article
- What Is the Role of [Open forum infectious diseases · 2024Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Fever of unknown origin (FUO) and inflammation of unknown origin (IUO) are syndromes commonly used as medical diagnoses. Since the existing literature has a mixture of diagnostic approaches, developing consensus-based recommendations would be helpful for clinicians, researchers, and patients. Methods: A modified Delphi process was performed from October 2022 to July 2023, involving 4 rounds of online surveys and 2 live video conferences. The panel comprised international experts recruited based on peer-reviewed published publications and studies. Results: Among 50 invited experts, 26 (52.0%) agreed to participate. Twenty-three panelists completed round 1 of the survey, 21 completed rounds 2 and 3, 20 completed round 4, and 7 participated in round 5 live video discussions. Of the participants, 18 (78.3%) were academic-based clinicians and researchers, 5 (21.7%) practiced in a community-based hospital, and 6 (26.1%) were female. Consensus was reached on 5 themes: (1) incorporating epidemiologic factors, such as geographic location and travel history; (2) updated criteria for classifying FUO or IUO; (3) initial evaluation approaches; (4) a classification system for diagnoses; and (5) recommendations for judicious limitation of empiric therapies. Experts strongly disagreed with using 2-deoxy-2-[ Conclusions: These Delphi-generated consensus-based recommendations offer potential improvements compared with earlier definitions and a guide for clinical practice and future research.
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