Evidence map›Paper›PMID 38966765›Full record

ArticleIJU case reports2024

Initial experience of enfortumab vedotin in a patient with metastatic urothelial carcinoma on hemodialysis: Two case reports.

Shintaro Mori, Tomohiro Matsuo, Hiroyuki Honda, Kyohei Araki, Kensuke Mitsunari, Kojiro Ohba, Yasushi Mochizuki, Ryoichi Imamura

Abstract readCase Reports
In one paragraph

Article in IJU case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Efficacy and Safety of Enfortumab Vedotin by Trial Eligibility in Advanced Urothelial Carcinoma: A Multicenter Real-World Study.International journal of urology : official journal of the Japanese Urological Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shintaro MoriDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.
Tomohiro MatsuoDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.ORCID https://orcid.org/0000-0002-9508-0319
Hiroyuki HondaDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.
Kyohei ArakiDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.
Kensuke MitsunariDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.ORCID https://orcid.org/0000-0002-6963-5632
Kojiro OhbaDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.ORCID https://orcid.org/0000-0003-2841-1998
Yasushi MochizukiDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.
Ryoichi ImamuraDepartment of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Few studies have reported on administering enfortumab vedotin to patients with metastatic urothelial carcinoma and end-stage renal disease requiring hemodialysis. Case presentation: Case 1: An 85-year-old man underwent hemodialysis for progressive renal failure 4 months after right laparoscopic radical nephroureterectomy. Case 2: A 73-year-old man underwent hemodialysis after two laparoscopic radical nephroureterectomies for recurrent urothelial carcinoma. In both cases, enfortumab vedotin was administered due to postoperative recurrence and progression despite platinum-based chemotherapy and pembrolizumab. Partial response and disease progression were observed in cases 1 and 2, respectively. Adverse events included a mild skin rash in both patients and neutropenia in Case 1, both of which resolved with symptomatic treatment. Conclusion: The efficacy and safety of enfortumab vedotin in patients with metastatic urothelial carcinoma, and end-stage renal disease undergoing hemodialysis, were confirmed.

Indexed as

end‐stage renal diseaseenfortumab vedotinhemodialysismetastatic urothelial carcinoma

Identifiers

PMID38966765
PMCPMC11221941

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.