Evidence map›Paper›PMID 38966581›Full record

ArticleOncology letters2024

Efficacy of venetoclax and rituximab in the treatment of concurrent acute myeloid leukemia and untreated chronic lymphocytic leukemia: A case report and literature review.

Yafang Chen, Linyu Yuan, Xinxiao Lu, Xue Wang, Qiuqiu Zhang, Xiaofang Wang, Xingli Zhao

Abstract readCase Reports
In one paragraph

Article in Oncology letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Multidrug Resistance: Are We Still Afraid of the Big Bad Wolf.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yafang ChenDepartment of Hematology, Oncology Center, Tianjin Union Medical Center of Nankai University, Tianjin 300121, P.R. China.
Linyu YuanDepartment of Hematology, Oncology Center, Tianjin Union Medical Center of Nankai University, Tianjin 300121, P.R. China.
Xinxiao LuDepartment of Hematology, Oncology Center, Tianjin Union Medical Center of Nankai University, Tianjin 300121, P.R. China.
Xue WangDepartment of Hematology, Oncology Center, Tianjin Union Medical Center of Nankai University, Tianjin 300121, P.R. China.
Qiuqiu ZhangDepartment of Hematology, Oncology Center, Tianjin Union Medical Center of Nankai University, Tianjin 300121, P.R. China.
Xiaofang WangDepartment of Hematology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, P.R. China.
Xingli ZhaoDepartment of Hematology, Oncology Center, Tianjin Union Medical Center of Nankai University, Tianjin 300121, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, few cases of concurrent acute myeloid leukemia (AML) and untreated chronic lymphocytic leukemia (CLL) have been reported. Due to the complexity of the pathogenesis and the absence of a uniform treatment regimen, the associated prognosis remains poor. The present study reports the case of a 58-year-old male with asymptomatic leukocytosis, who was previously healthy with no malignancies. Flow cytometry analysis revealed protocytosis, monocytosis and monoclonal B lymphocytosis in a bone marrow specimen. Results of a gene rearrangement assay demonstrated positive immunoglobulin heavy-chain variable region gene status in monoclonal B lymphocytes. Thus, the patient was diagnosed with AML with maturation (AML-M2) that co-existed with untreated CLL. The normative daunorubicin (40 mg/m

Indexed as

acute myeloid leukemiachronic lymphocytic leukemiacomplete remissionrituximabvenetoclax

Identifiers

PMID38966581
PMCPMC11223026

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.