Evidence map›Paper›PMID 38966375›Full record

ArticleChemical science2024

Mechanistic insights into bismuth(iii) inhibition of SARS-CoV-2 helicase.

Xueying Wei, Chun-Lung Chan, Ying Zhou, Kaiming Tang, Jingxin Chen, Suyu Wang, Jasper Fuk-Woo Chan, Shuofeng Yuan, Hongyan Li, Hongzhe Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Au(I)-based compounds inhibit nsp14/nsp10 and nsp13 (helicase) to exert anti-SARS-CoV-2 properties.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xueying WeiDepartment of Chemistry and CAS-HKU Joint Laboratory of Metallomics on Heath and Environment, The University of Hong Kong Pokfulam Hong Kong Special Administrative Region China hsun@hku.hk.ORCID https://orcid.org/0000-0002-6353-2763
Chun-Lung ChanDepartment of Chemistry and CAS-HKU Joint Laboratory of Metallomics on Heath and Environment, The University of Hong Kong Pokfulam Hong Kong Special Administrative Region China hsun@hku.hk.
Ying ZhouDepartment of Chemistry and CAS-HKU Joint Laboratory of Metallomics on Heath and Environment, The University of Hong Kong Pokfulam Hong Kong Special Administrative Region China hsun@hku.hk.
Kaiming TangDepartment of Microbiology and State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong Pokfulam Hong Kong Special Administrative Region China.
Jingxin ChenDepartment of Chemistry and CAS-HKU Joint Laboratory of Metallomics on Heath and Environment, The University of Hong Kong Pokfulam Hong Kong Special Administrative Region China hsun@hku.hk.ORCID https://orcid.org/0000-0002-6613-5245
Suyu WangDepartment of Chemistry and CAS-HKU Joint Laboratory of Metallomics on Heath and Environment, The University of Hong Kong Pokfulam Hong Kong Special Administrative Region China hsun@hku.hk.
Jasper Fuk-Woo ChanDepartment of Microbiology and State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong Pokfulam Hong Kong Special Administrative Region China.ORCID https://orcid.org/0000-0001-6336-6657
Shuofeng YuanDepartment of Microbiology and State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong Pokfulam Hong Kong Special Administrative Region China.ORCID https://orcid.org/0000-0001-7996-1119
Hongyan LiDepartment of Chemistry and CAS-HKU Joint Laboratory of Metallomics on Heath and Environment, The University of Hong Kong Pokfulam Hong Kong Special Administrative Region China hsun@hku.hk.ORCID https://orcid.org/0000-0002-1158-5871
Hongzhe SunDepartment of Chemistry and CAS-HKU Joint Laboratory of Metallomics on Heath and Environment, The University of Hong Kong Pokfulam Hong Kong Special Administrative Region China hsun@hku.hk.ORCID https://orcid.org/0000-0001-6697-6899

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic caused by SARS-CoV-2 resulted in a global public health crisis. In addition to vaccines, the development of effective therapy is highly desirable. Targeting a protein that plays a critical role in virus replication may allow pan-spectrum antiviral drugs to be developed. Among SARS-CoV-2 proteins, helicase (

Identifiers

PMID38966375
PMCPMC11220592

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.