Evidence map›Paper›PMID 38966174›Full record

ReviewExploration of targeted anti-tumor therapy2024

DNA damage targeted therapy for advanced breast cancer.

Vanessa Patel, Sandra Casimiro, Catarina Abreu, Tiago Barroso, Rita Teixeira de Sousa, Sofia Torres, Leonor Abreu Ribeiro, Gonçalo Nogueira-Costa, Helena Luna Pais, Conceição Pinto and 2 more

Abstract readReview
In one paragraph

Review in Exploration of targeted anti-tumor therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Role of PARP Inhibitors: A New Hope for Breast Cancer Therapy.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vanessa PatelOncology Division, Unidade Local de Saúde Santa Maria, 1649-028 Lisboa, Portugal.
Sandra CasimiroInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina de Lisboa, Universidade de Lisboa, 1649-028 Lisboa, Portugal.ORCID https://orcid.org/0000-0002-6917-4477
Catarina AbreuOncology Division, Unidade Local de Saúde Santa Maria, 1649-028 Lisboa, Portugal.ORCID https://orcid.org/0000-0003-3558-3966
Tiago BarrosoOncology Division, Unidade Local de Saúde Santa Maria, 1649-028 Lisboa, Portugal.
Rita Teixeira de SousaOncology Division, Unidade Local de Saúde Santa Maria, 1649-028 Lisboa, Portugal.
Sofia TorresOncology Division, Unidade Local de Saúde Santa Maria, 1649-028 Lisboa, Portugal.
Leonor Abreu RibeiroOncology Division, Unidade Local de Saúde Santa Maria, 1649-028 Lisboa, Portugal.
Gonçalo Nogueira-CostaOncology Division, Unidade Local de Saúde Santa Maria, 1649-028 Lisboa, Portugal.
Helena Luna PaisOncology Division, Unidade Local de Saúde Santa Maria, 1649-028 Lisboa, Portugal.
Conceição PintoOncology Division, Unidade Local de Saúde Santa Maria, 1649-028 Lisboa, Portugal.
Leila CostaPharmacy Department, Unidade Local de Saúde Santa Maria, 1649-028 Lisboa, Portugal.
Luís CostaOncology Division, Unidade Local de Saúde Santa Maria, 1649-028 Lisboa, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BC) is the most prevalent malignancy affecting women worldwide, including Portugal. While the majority of BC cases are sporadic, hereditary forms account for 5-10% of cases. The most common inherited mutations associated with BC are germline mutations in the BReast CAncer (BRCA) 1/2 gene (

Indexed as

breast cancerBReast CAncer 1/2 genechemotherapyhomologous recombinationpoly[adenosine diphosphate-ribose] polymerase

Identifiers

PMID38966174
PMCPMC11220312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.