Evidence map›Paper›PMID 38966077›Full record

ArticleOsteoarthritis and cartilage open2024

Planned or recent first consultation with the general practitioner for knee complaints: Is it indicative of early-stage knee osteoarthritis?

Nuria Ej Jansen, Dieuwke Schiphof, Jos Runhaar, Edwin Hg Oei, Sita Ma Bierma-Zeinstra, Marienke van Middelkoop

Abstract read
In one paragraph

Article in Osteoarthritis and cartilage open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nuria Ej JansenDepartment of General Practice, Erasmus MC University Medical Center Rotterdam, the Netherlands.
Dieuwke SchiphofDepartment of General Practice, Erasmus MC University Medical Center Rotterdam, the Netherlands.
Jos RunhaarDepartment of General Practice, Erasmus MC University Medical Center Rotterdam, the Netherlands.
Edwin Hg OeiDepartment of Radiology & Nuclear Medicine, Erasmus MC University Medical Center Rotterdam, the Netherlands.
Sita Ma Bierma-ZeinstraDepartment of General Practice, Erasmus MC University Medical Center Rotterdam, the Netherlands.
Marienke van MiddelkoopDepartment of General Practice, Erasmus MC University Medical Center Rotterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: No established definition for early-stage knee osteoarthritis (KOA) is available, nor classification criteria. Identifying the characteristics of individuals presenting with early-stage KOA symptoms can enhance diagnosis to prevent progression. This study aimed to describe clinical and structural features of individuals presenting with knee complaints within two years after their first consultation, while exploring differences in the duration of knee complaints. Method: Baseline data was used from the LITE randomized controlled trial, assessing the effectiveness of a lifestyle intervention for individuals with knee complaints and overweight in primary care. Baseline assessments included questionnaires, clinical assessment, and MRI of the most symptomatic knee. Differences between groups with varying durations of knee complaints (<12, ≥12-<24, ≥24 months) were evaluated. Results: Participants (N ​= ​218, 65% female, mean age 59 ​± ​6 years, mean BMI 32 ​± ​5 ​kg/m Conclusion: Within 24 months of initial consultation, over two-thirds of participants displayed MRI-defined structural KOA, and nearly half reported unacceptable symptom states. This study found no association between the duration of knee complaints and symptoms severity or structural KOA presence, underscoring the complexity of identifying stages of KOA among individuals with overweight. Future studies should explore additional features beyond current considerations to facilitate early-stage KOA diagnosis, specifically for individuals with overweight.

Indexed as

Diagnostic criteriaEarly-stageOverweightPrimary care

Identifiers

PMID38966077
PMCPMC11223112

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.