Evidence map›Paper›PMID 38966045›Full record

ArticleBioscience of microbiota, food and health2024

Continuous intake of galacto-oligosaccharides containing syrup contributes to maintaining the health of household dogs by modulating their gut microbiota.

Atsuko Hokkyo, Sayaka Kakiyama, Yuh Shiwa, Chiaki Kaga, Toshihide Kobayashi, Koji Nomoto, Naomi Harima-Mizusawa

Abstract read
In one paragraph

Article in Bioscience of microbiota, food and health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Use of Different Synbiotic Strategies to Improve Gut Health in Dogs.Animals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Atsuko HokkyoYakult Honsha Co., Ltd., Central Research Institute, 5-11 Izumi, Kunitachi-shi, Tokyo 186-8650, Japan.
Sayaka KakiyamaYakult Honsha Co., Ltd., Central Research Institute, 5-11 Izumi, Kunitachi-shi, Tokyo 186-8650, Japan.
Yuh ShiwaDepartment of Molecular Microbiology, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan.
Chiaki KagaYakult Honsha Co., Ltd., Central Research Institute, 5-11 Izumi, Kunitachi-shi, Tokyo 186-8650, Japan.
Toshihide KobayashiYakult Honsha Co., Ltd., Central Research Institute, 5-11 Izumi, Kunitachi-shi, Tokyo 186-8650, Japan.
Koji NomotoDepartment of Molecular Microbiology, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan.
Naomi Harima-MizusawaYakult Honsha Co., Ltd., Central Research Institute, 5-11 Izumi, Kunitachi-shi, Tokyo 186-8650, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interest is growing in the relationship of the microbiota and intestinal environment with health in companion animals. Galacto-oligosaccharides (GOS), typical prebiotics, are expected to provide benefits in dogs. Previous studies of GOS in dogs have involved dogs with similar rearing conditions and diets, which may have biased the results. We conducted an open study of 26 healthy dogs kept in households with diverse rearing environments in order to evaluate how the intake of a GOS-containing syrup affects the intestinal microbiota and its metabolites. Each dog was fed 1.2-4.8 g of the GOS-containing syrup (GOS 0.5-2.0 g equivalent) for 8 weeks. Fecal microbiota, fecal concentrations of organic acids and putrefactive products, fecal odor, and serum uremic toxin concentrations were evaluated before intake (0 weeks), during the 8-week intake period (4 and 8 weeks), and 4 weeks after intake (12 weeks). The activity of

Indexed as

doggalacto-oligosaccharidesmicrobiotaoral environmentorganic acidputrefactive productsuremic toxins

Identifiers

PMID38966045
PMCPMC11220336

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.