Evidence map›Paper›PMID 38965839›Full record

ArticleAmerican journal of hematology2024

Anxiety and depression are associated with heightened risk of incident deep vein thrombosis: Mediation through stress-related neural mechanisms.

Rachel P Rosovsky, Kenechukwu Mezue, Charbel Gharios, Giovanni Civieri, Alexander Cardeiro, Hadil Zureigat, Hui Chong Lau, Roger K Pitman, Lisa Shin, Shady Abohashem and 3 more

Abstract read
In one paragraph

Article in American journal of hematology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The relation between stress-related neural activity assessed by brainEuropean journal of nuclear medicine and molecular imaging · 2025
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rachel P RosovskyDepartment of Medicine, Division of Hematology/Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-2392-7365
Kenechukwu MezueCardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Charbel GhariosCardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-2262-4714
Giovanni CivieriCardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Alexander CardeiroCardiovascular Imaging Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Hadil ZureigatCardiovascular Imaging Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Hui Chong LauCardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Roger K PitmanDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA.
Lisa ShinDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA.
Shady AbohashemCardiovascular Imaging Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-5033-8881
Michael T OsborneCardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Farouc A JafferCardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Ahmed TawakolCardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Funding

Translational imaging and nanomedicine in inflammatory atherosclerosisP01HL131478 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Li Shen · 2017 to 2026
$24.3M
Novel PET/CT and Treatment Strategies to reduce PTS following DVTR01HL137913 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI JAFFER, FAROUC AMIN, TAWAKOL, AHMED A · 2017 to 2020
$3.3M
The Effect of Mindfulness on Vascular Inflammation in Stable Coronary Disease: A Multi-System PET/MRI StudyK23HL151909 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI OSBORNE, MICHAEL THOMAS · 2021 to 2025
$997k
Neuroimaging Measures of Psychological Distress as Predictors of Articular and Arterial Inflammation and Treatment Response in Rheumatoid ArthritisR56AR077187 · NIAMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GILES, JON T, TAWAKOL, AHMED A · 2020 to 2020
$555k
NHLBI NIH HHS K23 HL151909NHLBI NIH HHS P01 HL131478NHLBI NIH HHS R01 HL137913NIAMS NIH HHS R56 AR077187
6 · The paper itself

Abstract

Controversy exists as to whether anxiety and depression increase deep vein thrombosis (DVT) risk, and the mechanisms mediating potential links remain unknown. We aimed to evaluate the association between anxiety and depression and DVT risk and determine whether upregulated stress-related neural activity (SNA), which promotes chronic inflammation, contributes to this link. Our retrospective study included adults (N = 118 871) enrolled in Mass General Brigham Biobank. A subset (N = 1520) underwent clinical

Indexed as

AnxietyDepressionVenous ThrombosisAdultAgedAmygdalaC-Reactive ProteinFemaleHeart RateHumansIncidenceMaleMiddle AgedPositron Emission Tomography Computed TomographyRetrospective StudiesRisk FactorsC-Reactive Protein

Identifiers

PMID38965839
PMCPMC11502251

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.