Evidence map›Paper›PMID 38965573›Full record

ArticleBiological research2024

Lead and calcium crosstalk tempted acrosome damage and hyperpolarization of spermatozoa: signaling and ultra-structural evidences.

Rajkumar Singh Yadav, Bhawna Kushawaha, Rahul Dhariya, Dilip Kumar Swain, Brijesh Yadav, Mukul Anand, Priyambada Kumari, Pradeep Kumar Rai, Dipty Singh, Sarvajeet Yadav and 1 more

Abstract read
In one paragraph

Article in Biological research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rajkumar Singh YadavDepartment of Pharmacology and Toxicology, U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan, Mathura, India.
Bhawna KushawahaCollege of Biotechnology, Mathura, India. bhawnarajput31jan@gmail.com.ORCID http://orcid.org/0000-0002-6178-7068
Rahul DhariyaCollege of Biotechnology, Mathura, India.
Dilip Kumar SwainDepartment of Veterinary Physiology, U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan, Mathura, India.
Brijesh YadavDepartment of Veterinary Physiology, U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan, Mathura, India.
Mukul AnandDepartment of Veterinary Physiology, U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan, Mathura, India.
Priyambada KumariCollege of Biotechnology, Mathura, India.ORCID https://orcid.org/0000-0002-7218-8642
Pradeep Kumar RaiBD Bioscience, Gurgaon, India.
Dipty SinghICMR-National Institute for Research in Reproductive Health (NIRRH), Mumbai, India.ORCID https://orcid.org/0000-0002-3950-0083
Sarvajeet YadavDepartment of Veterinary Physiology, U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan, Mathura, India.
Satish Kumar GargDepartment of Pharmacology and Toxicology, U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan, Mathura, India. profsatish@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExposure of humans and animals to heavy metals is increasing day-by-day; thus, lead even today remains of significant public health concern. According to CDC, blood lead reference value (BLRV) ranges from 3.5 µg/dl to 5 μg/dl in adults. Recently, almost 2.6% decline in male fertility per year has been reported but the cause is not well established. Lead (Pb

resultsLead significantly decreased motility, viable count, and motion kinematic patterns of spermatozoa like curvilinear velocity, straight-line velocity, average path velocity, beat cross frequency and maximum amplitude of head lateral displacement even at 5 ppm concentration. Pb

conclusionsPb

Indexed as

AcrosomeAcrosome ReactionCalciumLeadSpermatozoaSperm MotilityAnimalsCattleCyclic AMPDNA DamageMaleMembrane Potential, MitochondrialOrganometallic CompoundsSemen AnalysisSignal TransductionCalciumCyclic AMPLeadlead acetateOrganometallic CompoundsCa2+ channelsCapacitation and electron microscopyDNA fragmentationLeadSpermatozoa

Identifiers

PMID38965573
PMCPMC11225213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.