Evidence map›Paper›PMID 38965444›Full record

ArticleNature methods2024

quantms: a cloud-based pipeline for quantitative proteomics enables the reanalysis of public proteomics data.

Chengxin Dai, Julianus Pfeuffer, Hong Wang, Ping Zheng, Lukas Käll, Timo Sachsenberg, Vadim Demichev, Mingze Bai, Oliver Kohlbacher, Yasset Perez-Riverol

Abstract read
In one paragraph

Article in Nature methods, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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  8. Navigating the conjugated metabolome.bioRxiv : the preprint server for biology · 2026
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  16. Genomic, Proteomic, and Biochemical Study ofJournal of agricultural and food chemistry · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chengxin Dai *Chongqing Key Laboratory of Big Data for Bio Intelligence, Chongqing University of Posts and Telecommunications, Chongqing, China.
Julianus Pfeuffer *Algorithmic Bioinformatics, Freie Universität Berlin, Berlin, Germany.
Hong WangChongqing Key Laboratory of Big Data for Bio Intelligence, Chongqing University of Posts and Telecommunications, Chongqing, China.
Ping ZhengChongqing Key Laboratory of Big Data for Bio Intelligence, Chongqing University of Posts and Telecommunications, Chongqing, China.
Lukas KällScience for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-5689-9797
Timo SachsenbergDepartment of Computer Science, Applied Bioinformatics, University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0002-2833-6070
Vadim DemichevCharité-Universitätsmedizin Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-2424-9412
Mingze BaiChongqing Key Laboratory of Big Data for Bio Intelligence, Chongqing University of Posts and Telecommunications, Chongqing, China.
Oliver KohlbacherDepartment of Computer Science, Applied Bioinformatics, University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0003-1739-4598
Yasset Perez-RiverolEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, UK. yperez@ebi.ac.uk.ORCID http://orcid.org/0000-0001-6579-6941

Funding

Wellcome TrustWellcome Trust (Wellcome) 208391/Z/17/Z
6 · The paper itself

Abstract

The volume of public proteomics data is rapidly increasing, causing a computational challenge for large-scale reanalysis. Here, we introduce quantms ( https://quant,ms.org/ ), an open-source cloud-based pipeline for massively parallel proteomics data analysis. We used quantms to reanalyze 83 public ProteomeXchange datasets, comprising 29,354 instrument files from 13,132 human samples, to quantify 16,599 proteins based on 1.03 million unique peptides. quantms is based on standard file formats improving the reproducibility, submission and dissemination of the data to ProteomeXchange.

Indexed as

Cloud ComputingProteomicsSoftwareComputational BiologyDatabases, ProteinHumansPeptidesProteomeReproducibility of ResultsPeptidesProteome

Identifiers

PMID38965444
PMCPMC11399091

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.