ArticlePediatric research2025
Long-term health in individuals born preterm or with low birth weight: A cohort study.
Article in Pediatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Residential greenness and birth outcomes: evidence for reduced low birth weight from an umbrella review and harmonized normalized difference vegetation index synthesis.Frontiers in public health · 2026Pooled it
- CONSTANCES, the French nationwide population cohort: major accomplishments.European journal of epidemiology · 2026Article
- Prenatal anxiety, tobacco use, and infant birth weight: a multilevel analysis of PRAMS data.Archives of women's mental health · 2026Article
- Early Childhood Obesity: Multifactorial Influences with a Prominent Familial ContributionJournal of clinical research in pediatric endocrinology · 2026Article
- Impact of Prematurity on Nutrient Signaling and Protein Synthesis in Skeletal Muscle.Annual review of nutrition · 2026Review
- Joint Associations of Maternal Smoking and Pre-Pregnancy BMI with Term Low Birthweight and Small-for-Gestational-Age Births: A Cross-Sectional Analysis of 2024 United States Birth Data.International journal of environmental research and public health · 2026Article
- Preterm birth and birth weight extremes are associated with periodontal disease and tooth loss in the ARIC study.Scientific reports · 2026Article
- Microplastics in Female Reproductive and Pregnancy Organs: A Systematic Review.Life (Basel, Switzerland) · 2026Review
- Optimal weight gain to reduce obesity risk in preterm infants in a National cohort study.Scientific reports · 2026Article
- Association of birth weight with lung function and the mediating role of gut microbiota: A STROBE 2-step Mendelian randomization study.Medicine · 2025Article
- Consanguineous marriages and low birth weight mediating role of antenatal care visits.Scientific reports · 2025Article
- Associations of maternal neighborhood and trauma-related stressors with mitochondrial DNA copy number and telomere length in maternal and cord blood.Scientific reports · 2025Article
- Predicting Low Birth Weight in Big Cities in the United States Using a Machine Learning Approach.International journal of environmental research and public health · 2025Article
- Surviving prematurity: retrospective longitudinal study of multisystem consequences in preterm-born individuals from infancy to adolescence.BMC pediatrics · 2025Article
- Examining the combined effect of antenatal care visits and iron-folic acid supplementation on low birth weight: a pooled analysis of two national data sets from Nepal.BMC pregnancy and childbirth · 2024Article
- A Multicenter Phase II Study on Photodynamic Therapy Using Talaporfin Sodium (ME2906) and a Semiconductor Laser (PNL6405CIN) for Intraepithelial Tumors of the Cervix.Reproductive medicine and biologyArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo measure the association of prematurity and non-preterm low birth weight (LBW) with several long-term health outcomes.
methodsWe selected adult participants from the Constances cohort. Associations between preterm birth (<37 weeks versus ≥37 weeks) and outcomes were measured using modified Poisson regression with adjustment for participant age and parental history. We used the same modeling methods to measure the association between LBW (i.e., <sex-specific 10th percentile) and outcomes in participants born ≥ 37 weeks. We tested for an interaction between exposures and sex.
resultsAmong 30,295 participants, preterm birth (5.2%) was associated with (RR[CI95]): obesity (1.25[1.08-1.46]), hypertriglyceridemia (1.23[1.07-1.42]), high LDL-cholesterol (1.16[1.05-1.28]), high blood pressure (HBP) (1.22[1.08-1.36]), metabolic syndrome (1.35[1.06-1.71]), non-alcoholic fatty liver disease (1.26[1.08-1.47]), allergic and atopic symptoms (1.06[1.01-1.12]), and lack of tertiary education (1.11[1.02-1.20]). Women had a significantly higher risk of hypertriglyceridemia and metabolic syndrome. In non-preterm participants, LBW was associated with prediabetes/diabetes (1.30[1.12-1.52]), HBP (1.22[(1.12-1.33]) and lack of tertiary education (1.13[1.07-1.20]), whereas the risk of obesity (0.83[0.73-0.95]) and abdominal obesity (0.84[0.76-0.93]) was reduced.
conclusionPreterm birth and non-preterm LBW are both risk factors for several adult outcomes. However, regarding excess fat storage, their long-term effect seems to be in the opposite direction. IMPACT STATEMENT: Preterm birth is associated with a higher long-term risk of obesity, whereas low birth weight is not. This study improves the understanding of the common idea that low birth weight is associated with a long-term risk of obesity, whereas it might depend on the cause of low birth weight. These findings provide new insights into the difficult distinction between the long-term adverse health effects of preterm birth and low birth weight.
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