Evidence map›Paper›PMID 38965271›Full record

ArticleScientific reports2024

Impaired metal perception and regulation of associated human foliate papillae tongue transcriptome in long-COVID-19.

Barbara Danzer, Mateo Jukic, Andreas Dunkel, Gaby Andersen, Barbara Lieder, Erika Schaudy, Sarah Stadlmayr, Jory Lietard, Timm Michel, Dietmar Krautwurst and 5 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Barbara DanzerSchool of Life Science, Technical University of Munich, Freising, Germany.
Mateo JukicDepartment of Neurology, School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Andreas DunkelLeibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany.
Gaby AndersenLeibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany.
Barbara LiederDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria.
Erika SchaudyDepartment of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria.
Sarah StadlmayrDepartment of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria.
Jory LietardDepartment of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria.
Timm MichelSchool of Life Science, Technical University of Munich, Freising, Germany.
Dietmar KrautwurstLeibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany.
Bernhard HallerInstitute of AI and Informatics in Medicine, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Percy KnolleInstitute of Molecular Immunology, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Mark SomozaLeibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany.
Paul Lingor *Department of Neurology, School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Veronika Somoza *Leibniz Institute for Food Systems Biology at the Technical University of Munich, Freising, Germany. v.somoza.leibniz-lsb@tum.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemosensory impairment is an outstanding symptom of SARS-CoV-2 infections. We hypothesized that measured sensory impairments are accompanied by transcriptomic changes in the foliate papillae area of the tongue. Hospital personnel with known SARS-CoV-2 immunoglobulin G (IgG) status completed questionnaires on sensory perception (n = 158). A subcohort of n = 141 participated in forced choice taste tests, and n = 43 participants consented to donate tongue swabs of the foliate papillae area for whole transcriptome analysis. The study included four groups of participants differing in IgG levels (≥ 10 AU/mL = IgG

Indexed as

COVID-19SARS-CoV-2TongueTranscriptomeAdultFemaleHumansImmunoglobulin GMaleMetalsMiddle AgedOlfactory PerceptionReceptors, OdorantTasteTaste BudsTaste PerceptionImmunoglobulin GMetalsReceptors, Odorant

Identifiers

PMID38965271
PMCPMC11224223

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.