ArticleClinical oral investigations2024
Biofilm inhibition of denture cleaning tablets and carvacrol on denture bases produced with different techniques.
Article in Clinical oral investigations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Beyond roughness: Lateral surface architecture drives Candida albicans virulence on denture polymers.Dental materials : official publication of the Academy of Dental Materials · 2026Article
- Influence of Denture Base Fabrication onDentistry journal · 2026Article
- Assessment of mechanical, physical, and antimicrobial properties of tissue conditioners incorporated with plant extracts.Odontology · 2026Article
- In-vitro evaluation of the effectiveness of various disinfection procedures in reducing biofilm formation on customized implant abutments of different designs.Scientific reports · 2026Article
- Role of Carvacrol in Oral Health: An Overview.Current pharmaceutical design · 2026Review
- Effect of prolonged brushing with different agents on surface characteristics of conventional and 3D-printed denture resins.Scientific reports · 2025Article
- Characteristics of Acrylic Produced Additively by 3D Printing in Dentistry: Comparison of Mechanical and Surface Parameters-A Systematic Review with Meta-Analysis of Novel Reports.Materials (Basel, Switzerland) · 2025Review
- Effects ofInternational journal of dentistry · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study compares the biofilm inhibition effects of denture cleaning tablets, carvacrol, and their combined use against Candida albicans on denture bases produced with different techniques. Additionally, the surface roughness and contact angles of these denture bases were evaluated. MATERIALS AND
methodsTest samples were prepared from four different denture base materials (cold-polymerized, heat-polymerized, CAD/CAM milling, and 3D-printed). The surface roughness and contact angles of the test samples were measured using a profilometer and goniometer, respectively. For the evaluation of biofilm inhibition, samples were divided into 5 subgroups: Corega and carvacrol, separately and combined treatments, positive (inoculated with C. albicans) and negative control (non-inoculated with C. albicans, only medium). Biofilm mass was determined using the crystal violet method. An additional prepared test sample for each subgroup was examined under scanning electron microscopy (SEM).
resultsThe surface roughness values of the 3D-printed test samples were found to be statistically higher than the other groups (P < .001). The water contact angle of all test materials was not statistically different from each other (P > .001). Corega and carvacrol, separately and combined, significantly decreased the amount of biofilm on all surfaces (P < .0001). Treatment of corega alone and in combination with carvacrol to the 3D-printed material caused less C. albicans inhibition than the other groups (P < .001; P < .05).
conclusionsThe surface roughness values of all test groups were within the clinically acceptable threshold. Although Corega and carvacrol inhibited C. albicans biofilms, their combined use did not show a synergistic effect. CLINICAL RELEVANCE: Carvacrol may be used as one of the disinfectant agents for denture cleaning due to its biofilm inhibition property.
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