Evidence map›Paper›PMID 38965086›Full record

ArticleInternational ophthalmology2024

Vitamin D alleviation of oxidative stress in human retinal pigment epithelial cells.

Xiaolong Yang, Xing Qi, Kun Zuo, Yi Huang, Xiyun Bian, Jing Wang, Hao Yu, Qinbei Feng, Xia Lei, Tingli Chen

Abstract read
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In one paragraph

Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaolong Yang *Department of Ophthalmology, Huadong Sanatorium, Wuxi, 214000, China.
Xing Qi *Department of Otolaryngology, Huadong Sanatorium, Wuxi, 214000, China.
Kun Zuo *College of Pharmacy, Jia Mu Si University, Jiamusi, 154100, China.
Yi HuangDepartment of Ophthalmology, Huadong Sanatorium, Wuxi, 214000, China.
Xiyun BianDepartment of Ophthalmology, Huadong Sanatorium, Wuxi, 214000, China.
Jing WangDepartment of Ophthalmology, Huadong Sanatorium, Wuxi, 214000, China.
Hao YuCollege of Pharmacy, Jia Mu Si University, Jiamusi, 154100, China.
Qinbei FengDepartment of Medical Laboratory, Huadong Sanatorium, Wuxi, 214000, China.
Xia LeiWuxi Hospital of Traditional Chinese Medicine, Wuxi, 214071, Jiangsu, China. wxzy094@njucm.edu.cn.
Tingli ChenDepartment of Ophthalmology, Huadong Sanatorium, Wuxi, 214000, China. chentingli1028@163.com.

Funding

the Clinical Special Program of Shanghai Municipal Health Commission 20204Y0199, 20224044
6 · The paper itself

Abstract

backgroundOxidative stress-induced retinal pigment epithelium (RPE) cell damage is a major factor in age-related macular degeneration (AMD). Vitamin D

methodsHuman retinal pigment epithelial cell 19 (ARPE-19) cells were divided into four groups: blank group (untreated), model group (incubated in medium with 400 μmol/L H

resultsWe first established an ARPE-19 cell stress model with H

conclusionVD

Indexed as

ApoptosisCell SurvivalOxidative StressRetinal Pigment EpitheliumAntioxidantsCell LineCells, CulturedCellular SenescenceHumansHydrogen PeroxideMacular DegenerationReactive Oxygen SpeciesSirtuin 1Vitamin DVitaminsAntioxidantsHydrogen PeroxideReactive Oxygen SpeciesSIRT1 protein, humanSirtuin 1Vitamin DVitaminsAMDOxidative stressVD3

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.