Evidence map›Paper›PMID 38964784›Full record

ArticleJournal for immunotherapy of cancer2024

Unique immune characteristics and differential anti-PD-1-mediated reinvigoration potential of CD8

Junsik Park, Jung Chul Kim, Yong Jae Lee, Sunghoon Kim, Mi-Kyoung Seo, Sang Wun Kim, Eui-Cheol Shin, Jung Yun Lee, Su-Hyung Park

Erratum issuedAbstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Junsik ParkDepartment of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea (the Republic of).ORCID http://orcid.org/0000-0003-4094-2097
Jung Chul KimDepartment of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea (the Republic of).
Yong Jae LeeDepartment of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea (the Republic of).
Sunghoon KimDepartment of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea (the Republic of).
Mi-Kyoung SeoDepartment of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea (the Republic of).
Sang Wun KimDepartment of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea (the Republic of).
Eui-Cheol ShinGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea (the Republic of).
Jung Yun LeeDepartment of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea (the Republic of) jungyunlee@yuhs.ac park3@kaist.ac.kr.
Su-Hyung ParkGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea (the Republic of) jungyunlee@yuhs.ac park3@kaist.ac.kr.ORCID http://orcid.org/0000-0001-6363-7736

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to investigate the distinct immunological characteristics of the tumor immune microenvironment in epithelial ovarian cancer (EOC) according to

methodsTumor-infiltrating lymphocytes (TILs) were collected from patients with newly diagnosed advanced-stage EOC (YUHS cohort, n=117). This YUHS cohort was compared with The Cancer Genome Atlas (TCGA) data for ovarian serous cystadenocarcinoma (n=482), in terms of survival outcomes and immune-related gene profiles according to

resultsWe found that EOC patients with

conclusionOur results highlight unique immune features of CD8

Indexed as

BRCA1 ProteinCarcinoma, Ovarian EpithelialCD8-Positive T-LymphocytesLymphocytes, Tumor-InfiltratingMutationAdultAgedBRCA2 ProteinFemaleHumansImmune Checkpoint InhibitorsMiddle AgedOvarian NeoplasmsProgrammed Cell Death 1 ReceptorTumor MicroenvironmentBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, humanImmune Checkpoint InhibitorsPDCD1 protein, humanProgrammed Cell Death 1 ReceptorImmune Checkpoint InhibitorOvarian CancerTumor infiltrating lymphocyte - TIL

Identifiers

PMID38964784
PMCPMC11227838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.