Evidence map›Paper›PMID 38964743›Full record

ReviewRadiation research2024

An Overview of Radiation Countermeasure Development in Radiation Research from 1954 to 2024.

Juliann G Kiang, Georgetta Cannon, Vijay K Singh

Abstract readReviewHistorical Article
In one paragraph

Review in Radiation research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Radiomitigators: Breakthroughs in Post-Radiation Recovery.Antioxidants (Basel, Switzerland) · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juliann G KiangScientific Research Department, Armed Forces Radiobiology Research Institute.
Georgetta CannonScientific Research Department, Armed Forces Radiobiology Research Institute.
Vijay K SinghScientific Research Department, Armed Forces Radiobiology Research Institute.

Funding

Sample Engineering CoreU19AI067773 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI AMUNDSON, SALLY A. · 2005 to 2024
$105.4M
Ciprofloxacin enhances DNA repair capacity after radiation combined injuryR33AI080553 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI KIANG, JULIANN GONG · 2010 to 2012
$1.1M
NIAID 5U19AI067773-18, AND AFRRI AFR-B2-12812.NIAID R33-AI080553, JPC-6/7NIAID NIH HHS R33 AI080553NIAID NIH HHS U19 AI067773
6 · The paper itself

Abstract

Preparation for medical responses to major radiation accidents, further driven by increases in the threat of nuclear warfare, has led to a pressing need to understand the underlying mechanisms of radiation injury (RI) alone or in combination with other trauma (combined injury, CI). The identification of these mechanisms suggests molecules and signaling pathways that can be targeted to develop radiation medical countermeasures. Thus far, the United States Food and Drug Administration (U.S. FDA) has approved seven countermeasures to mitigate hematopoietic acute radiation syndrome (H-ARS), but no drugs are available for prophylaxis and no agents have been approved to combat the other sub-syndromes of ARS, let alone delayed effects of acute radiation exposure or the effects of combined injury. From its inception, Radiation Research has significantly contributed to the understanding of the underlying mechanisms of radiation injury and combined injury, and to the development of radiation medical countermeasures for these indications through the publication of peer-reviewed research and review articles.

Indexed as

Acute Radiation SyndromeAnimalsHistory, 20th CenturyHistory, 21st CenturyHumansMedical CountermeasuresRadiation InjuriesRadiation-Protective AgentsUnited StatesRadiation-Protective Agents

Identifiers

PMID38964743
PMCPMC11385179

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.