Evidence map›Paper›PMID 38963596›Full record

ArticleBulletin of experimental biology and medicine2024

TGFβ1 Regulates Cellular Composition of In Vitro Cardiac Perivascular Niche Based on Cardiospheres.

Yu D Goltseva, K V Dergilev, M A Boldyreva, E V Parfyonova, I B Beloglazova

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu D GoltsevaNational Medical Research Centre of Cardiology named after academician E. I. Chazov, Moscow, Russia. eleagnusom@gmail.com.
K V DergilevNational Medical Research Centre of Cardiology named after academician E. I. Chazov, Moscow, Russia.
M A BoldyrevaNational Medical Research Centre of Cardiology named after academician E. I. Chazov, Moscow, Russia.
E V ParfyonovaNational Medical Research Centre of Cardiology named after academician E. I. Chazov, Moscow, Russia.
I B BeloglazovaNational Medical Research Centre of Cardiology named after academician E. I. Chazov, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cardiac perivascular niche is a cellular microenvironment of a blood vessel. The principles of niche regulation are still poorly understood. We studied the effect of TGFβ1 on cells forming the cardiac perivascular niche using 3D cell culture (cardiospheres). Cardiospheres contained progenitor (c-Kit), endothelial (CD31), and mural (αSMA) cells, basement membrane proteins (laminin) and extracellular matrix proteins (collagen I, fibronectin). TGFβ1 treatment decreased the length of CD31

Indexed as

Cell DifferentiationCell ProliferationTransforming Growth Factor beta1AnimalsAntigens, CDCadherin 5CadherinsCell Culture Techniques, Three DimensionalCells, CulturedCollagen Type IEndothelial CellsFibronectinsHumansHuman Umbilical Vein Endothelial CellsLamininMicrofilament ProteinsAntigens, CDCadherin 5CadherinsCollagen Type IFibronectinsLamininMicrofilament ProteinsMuscle ProteinsPlatelet Endothelial Cell Adhesion Molecule-1Transforming Growth Factor beta1transgelincardiospherescell microenvironmentendotheliumperivascular nicheTGFβ1

Identifiers

PMID38963596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.