Evidence map›Paper›PMID 38963105›Full record

ArticleAnti-cancer agents in medicinal chemistry2024

Soudeh Khanamani Falahati-Pour, Seyedeh Atekeh Torabizadeh, Fatemeh Baghery, Mojgan Noroozi-Karimabad

Abstract read
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Article in Anti-cancer agents in medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. An Analysis of ThreeCurrent issues in molecular biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Soudeh Khanamani Falahati-PourPistachio Safety Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.ORCID 0000-0002-3539-8982
Seyedeh Atekeh TorabizadehDepartment of Medicinal Chemistry, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran.
Fatemeh BagheryPistachio Safety Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.ORCID 0000-0002-7273-3487
Mojgan Noroozi-KarimabadMolecular Medicine Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMany bioactive phytochemicals have essential significance for handling various diseases and developing new drugs. The aim was to investigate the anti-tumor activity and the underlying mechanisms of pistachio pericarp extract (PPE) and pistachio kernel extract (PKE) alone and combined with cisplatin (CP) in the treatment of prostate cancer.

methodsThe effects of the PPE, PKE, and CP alone and PPE and PKE in combination with CP (PPE+CP and PKE+CP) on the proliferation of PC-3 cells were determined using the MTT assay. The fold changes of

resultsThese research results indicated that a greater anti-proliferative effect of the PPE and PKE was shown in combination with CP compared with treatments using the PPE and PKE or CP alone. The extracts and Cisplatin

conclusionsThe finding of this research showed for the first time the anti-carcinogenesis effects of separately and in the combination of PPE, PKE, and CP on the PC-3 prostate cancer cells via modulating some genes and that it may be nominated for the herbal anti-cancer medications.

Indexed as

ApoptosisCell ProliferationCisplatinDrug Screening Assays, AntitumorPistaciaAntineoplastic AgentsAntineoplastic Agents, PhytogenicDose-Response Relationship, DrugHumansMaleMolecular StructurePlant ExtractsProstatic NeoplasmsStructure-Activity RelationshipTumor Cells, CulturedAntineoplastic AgentsAntineoplastic Agents, PhytogenicCisplatinPlant ExtractsCisplatingene expressionphytochemicals.pistaciaprostate anti-cancersynergistic

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.