Evidence map›Paper›PMID 38962911›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Biomimetic Metal-Organic Framework Gated Nanoplatform for Sonodynamic Therapy against Extensively Drug Resistant Bacterial Lung Infection.

Jianling Huang, Xiuwen Hong, Sixi Chen, Yucong He, Lixu Xie, Fenglin Gao, Chenghua Zhu, Xiao Jin, Haihao Yan, Yongxia Ye and 3 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Biomimetic materials for medical applications.Chinese medical journal · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Overcoming Methicillin-ResistantResearch (Washington, D.C.) · 2026
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jianling HuangDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China.
Xiuwen HongDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China.
Sixi ChenDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China.
Yucong HeDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China.
Lixu XieDepartment of Pulmonary and Critical Care Medicine, Qi Lu Hospital of Shandong University, Wen hua xi Road 107#, Jinan, 250012, China.
Fenglin GaoDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China.
Chenghua ZhuDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China.
Xiao JinDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China.
Haihao YanDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China.
Yongxia YeDepartment of Radiology, Nanjing Medical University Affiliated Cancer Hospital, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing, Jiangsu, 210009, China.
Mingyue ShaoDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China.
Xingran DuDepartment of Respiratory and Critical Care Medicine, The Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing, 211100, China.ORCID 0000-0003-3964-2070
Ganzhu FengDepartment of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, China.ORCID 0000-0003-3926-1753

Funding

Beijing Medical and Health Foundation BXS1-22003National Natural Science Foundation of China 82070017National Natural Science Foundation of China 82100014National Natural Science Foundation of China 82370014The Medical-Industrial Integration Project of the Second Affiliated Hospital of Nanjing Medical University TGRH012
6 · The paper itself

Abstract

Novel antimicrobial strategies are urgently needed to treat extensively drug-resistant (XDR) bacterial infections due to the high mortality rate and lack of effective therapeutic agents. Herein, nanoengineered human umbilical cord mesenchymal stem cells (hUC-MSCs), named PMZMU, are designed as a sonosensitizer for synergistic sonodynamic-nano-antimicrobial therapy against gram-negative XDR bacteria. PMZMU is composed of a bacterial targeting peptide (UBI

Indexed as

Anti-Bacterial AgentsMetal-Organic FrameworksAnimalsBiomimetic MaterialsBiomimeticsDisease Models, AnimalDrug Resistance, Multiple, BacterialHumansMesenchymal Stem CellsMiceNanoparticlesPseudomonas aeruginosaUltrasonic TherapyAnti-Bacterial AgentsMetal-Organic Frameworksbiomimetic nanoplatformextensively drug resistant bacteriamesenchymal stem cellsmetal–organic frameworkpolymyxin Bsonodynamic therapy

Identifiers

PMID38962911
PMCPMC11434100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.