Evidence map›Paper›PMID 38962840›Full record

ArticleEuropean journal of neurology2024

Deep abdominal breathing reduces heart rate and symptoms during orthostatic challenge in patients with postural orthostatic tachycardia syndrome.

Moritz Stick, Ariane Leone, Fiona Fischer, Jörg B Schulz, Andrea Maier

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Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Moritz StickDepartment of Neurology, Medical Faculty Rheinisch Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
Ariane LeoneDepartment of Pediatrics, München Rechts der Isar (MRI) Chronic Fatigue Center for Young People, University Hospital, Technical University of Munich, Munich, Germany.
Fiona FischerDepartment of Neurology, Medical Faculty Rheinisch Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
Jörg B SchulzDepartment of Neurology, Medical Faculty Rheinisch Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.
Andrea MaierDepartment of Neurology, Medical Faculty Rheinisch Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.ORCID 0000-0002-3427-4806

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThis study investigated the effects of deep abdominal breathing on cardiovascular parameters and symptoms in patients with postural orthostatic tachycardia syndrome (POTS) during head-up tilt-table (HUT) challenge.

methodsThirty POTS patients completed two consecutive rounds of 10-min HUT in a crossover design. One round was HUT without intervention, and one round combined the HUT with deep breathing at a rate of 6 breaths/min. Cardiovascular parameters, including mean blood pressure and maximum and mean heart rate (HR), were measured supine and standing. Symptoms were assessed using the Vanderbilt Orthostatic Symptom Score (VOSS).

resultsDuring the breathing technique, the mean HR increase was -7.35 bpm (95% confidence interval [CI] = -11.71 to -2.98), and the maximum HR increase was -6.27 bpm (95% CI = -11.85 to -0.68, p = 0.041), significantly lower compared to normal breathing. Additionally, improvements were observed in all absolute cardiovascular parameters during standing, with VOSS symptoms simultaneously and significantly decreasing by -5.38 (95% CI = -10.43 to -0.36).

conclusionsSlow deep abdominal breathing can act as a simple technique to reduce the standing HR increase upon HUT in patients with POTS. This suggests that modulation of the cardiopulmonary neurocircuits and the respiratory pump may reduce HR increase and symptoms in patients with POTS. The findings of this study highlight the use of a safe, zero-cost, and simple behavioral tool to suggest to POTS patients for symptom relief apart from standard treatment. The observed improvements in cardiovascular parameters and symptoms offer a promising therapeutic approach for patients in times of inadequate treatment options.

Indexed as

Cross-Over StudiesHeart RatePostural Orthostatic Tachycardia SyndromeTilt-Table TestAdultBlood PressureFemaleHumansMaleRespirationYoung Adultbreathing techniquedeep abdominal breathingheart ratepostural tachycardia syndromeVanderbilt Orthostatic Symptom Scoreyoga

Identifiers

PMID38962840
PMCPMC11414806

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.