Evidence map›Paper›PMID 38962751›Full record

ArticleNeuro-oncology advances

Medulloblastomas with

Léa Guerrini-Rousseau, Julien Masliah-Planchon, Mathilde Filser, Arnault Tauziède-Espariat, Natacha Entz-Werle, Christine M Maugard, Saskia M J Hopman, Jacob Torrejon, Marion Gauthier-Villars, Fatoumata Simaga and 27 more

Abstract read
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Germline Variants in Pediatric Cancer : Based on Oncogenic Pathways.Journal of Korean Neurosurgical Society · 2025
    Article
  6. Evolutionary evidence precludesNeuro-oncology advances
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Léa Guerrini-RousseauMolecular Predictors and New Targets in Oncology, Inserm U981 Team "Genomics and Oncogenesis of Pediatric Brain Tumors," Gustave Roussy, Université Paris-Saclay, Villejuif, France.ORCID https://orcid.org/0000-0003-0050-5407
Julien Masliah-PlanchonDepartment of Pathology and Diagnostic, Prognostic and Theranostic Medicine, Somatic Genetic Unit, Institut Curie, Paris Sciences Lettres Research University, Paris, France.
Mathilde FilserDepartment of Pathology and Diagnostic, Prognostic and Theranostic Medicine, Somatic Genetic Unit, Institut Curie, Paris Sciences Lettres Research University, Paris, France.
Arnault Tauziède-EspariatDepartment of Neuropathology, Sainte Anne Hospital, Paris, France.
Natacha Entz-WerlePediatric Hematology and Oncology Department, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.
Christine M MaugardDepartment of Clinical Genetics, Strasbourg University Hospital, Strasbourg, France.
Saskia M J HopmanDepartment of Genetics, University Medical Center Utrecht, Utrecht, the Netherlands.
Jacob TorrejonUniversité Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France.
Marion Gauthier-VillarsDepartment of Genetics, Institut Curie, Paris Sciences Lettres Research University, Paris, France.
Fatoumata SimagaDepartment of Genetics, Institut Curie, Paris Sciences Lettres Research University, Paris, France.
Thomas BlauwblommeNecker-Enfants Malades University Hospital, Department of Pediatric Neurosurgery, Paris-Cité University, Paris, France.ORCID https://orcid.org/0000-0003-4076-9642
Kevin BeccariaNecker-Enfants Malades University Hospital, Department of Pediatric Neurosurgery, Paris-Cité University, Paris, France.ORCID https://orcid.org/0000-0002-3405-1944
Etienne RouleauCancer Genetics Unit, Department of Biology and Pathology, Institut Gustave Roussy, Villejuif, France.ORCID https://orcid.org/0000-0002-9046-257X
Marina DimariaDepartment of Children and Adolescents Oncology, Gustave Roussy, Université Paris-Saclay, Villejuif, France.
Jacques GrillMolecular Predictors and New Targets in Oncology, Inserm U981 Team "Genomics and Oncogenesis of Pediatric Brain Tumors," Gustave Roussy, Université Paris-Saclay, Villejuif, France.ORCID https://orcid.org/0000-0003-4773-3001
Samuel AbbouDepartment of Children and Adolescents Oncology, Gustave Roussy, Université Paris-Saclay, Villejuif, France.
Béatrice ClaretPsycho-Oncology Unit, Interdisciplinary Department of Supportive Care, Gustave Roussy, Université Paris-Saclay, Villejuif, France.
Laurence BrugièresDepartment of Children and Adolescents Oncology, Gustave Roussy, Université Paris-Saclay, Villejuif, France.
François DozUniversité Paris Cité, SIREDO Pediatric Cancer Center, Institut Curie, Paris, France.ORCID https://orcid.org/0000-0001-9286-4831
Yassine BouchouchaSIREDO Center (Care, Innovation Research in Pediatric, Adolescent and Young Adult Oncology), Institut Curie, Paris, France.
Cécile Faure-ConterPediatric Hematology and Oncology Institut, Centre Léon Berard, Lyon, France.
Valerie BonadonaClinical Oncogenetics Unit, Department of Prevention and Public Health, Centre Léon Bérard, Lyon, France.
Ludovic MansuyDepartment of Pediatric Hematology and Oncology, Centre Hospitalo-Universitaire de Nancy, Vandœuvre-lès-Nancy, France.
Emilie de CarliPediatric Hematology and Oncology Department, Angers University Hospital, Nancy, France.
Olivier IngsterDepartment of Genetics, Angers University Hospital, Angers, France.
Clémentine LegrandDepartment of Genetics, Grenoble University Hospital, Grenoble, France.
Anne PagnierDepartment of Pediatric Hematology and Oncology, Centre Hospitalo-Universitaire de Grenoble, Grenoble, France.
Pascaline BerthetDepartment of Genetics, Centre François Baclesse, Caen, France.
Damien BodetPediatric Hematology and Oncology Department, Caen University Hospital, Caen, France.
Sophie JuliaDepartment of Genetics, Toulouse University Hospital, Toulouse, France.
Anne-Isabelle BertozziPediatric Hematology and Oncology Department, Toulouse University Hospital, Toulouse, France.
Marjolaine WilemsDepartment of Medical Genetics, Montpellier University Hospital, Institute for Neurosciences of Montpellier, Univ Montpellier, INSERM, Montpellier, France.
Claude-Alain MaurageLaboratory of Neuropathology, Centre Oscar Lambret, Lille, France.
Olivier DelattreINSERM U830, Cancer, Heterogeneity, Instability and Plasticity Laboratory Institut Curie, Paris, France.
Olivier AyraultUniversité Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France.
Christelle DufourMolecular Predictors and New Targets in Oncology, Inserm U981 Team "Genomics and Oncogenesis of Pediatric Brain Tumors," Gustave Roussy, Université Paris-Saclay, Villejuif, France.ORCID https://orcid.org/0000-0001-5993-8077
Franck BourdeautUniversité Paris Cité, SIREDO Pediatric Cancer Center, Institut Curie, Paris, France.ORCID https://orcid.org/0000-0001-9489-6781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: We retrospectively reviewed clinical and genetic data of a French series of 29 Results: All patients developed SHH-MB, with a biallelic inactivation of Conclusions: The low penetrance, the "at risk' age window limited to childhood and the narrow tumor spectrum, question the actual benefit of genetic screening in these patients and their family. Our results suggest restricting

Indexed as

cancer predisposition syndromeELP1medulloblastomapathogenic variant

Identifiers

PMID38962751
PMCPMC11221071

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.