Evidence map›Paper›PMID 38962597›Full record

ArticleCureus2024

Disseminated Cryptococcosis With Prostate Involvement in a Patient With T-cell Prolymphocytic Leukemia and Prostate Cancer.

Anastasios Ioannidis, Charalampos Mavridis, Georgios Anagnostakis, Georgia Tsoumi, Stamatis Karakonstantis, Irene Xylouri, Elias Drakos, Charalampos Mamoulakis

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anastasios IoannidisUrology Department, University General Hospital of Heraklion, University of Crete Medical School, Heraklion, GRC.
Charalampos MavridisUrology Department, University General Hospital of Heraklion, University of Crete Medical School, Heraklion, GRC.
Georgios AnagnostakisHematology Department, University General Hospital of Heraklion, University of Crete Medical School, Heraklion, GRC.
Georgia TsoumiInternal Medicine Department, University General Hospital of Heraklion, University of Crete Medical School, Heraklion, GRC.
Stamatis KarakonstantisInternal Medicine Department, University General Hospital of Heraklion, University of Crete Medical School, Heraklion, GRC.
Irene XylouriHematology Department, University General Hospital of Heraklion, University of Crete Medical School, Heraklion, GRC.
Elias DrakosPathology Department, University General Hospital of Heraklion, University of Crete Medical School, Heraklion, GRC.
Charalampos MamoulakisUrology Department, University General Hospital of Heraklion, University of Crete Medical School, Heraklion, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T-cell prolymphocytic leukemia (T-PLL) presents unique treatment challenges because of its rarity and aggressiveness. Allogeneic hematopoietic stem cell transplantation offers a potentially curative option, but its safety in patients with concurrent invasive fungal infections and solid malignancies remains uncertain. We present a case of a 68-year-old male with T-PLL who developed disseminated cryptococcal disease with prostate involvement and concurrent prostate cancer (PCa). Despite the challenges, successful control of the infection and radical prostatectomy enabled the patient to proceed safely to allogeneic transplantation. The case highlights the importance of vigilance for unusual infections, such as Cryptococcus, in immunocompromised patients presenting with lower urinary tract symptoms. Clinicians should consider the possibility of PCa in this population, particularly in the context of chronic leukemia. Concurrently, the potential association between fungal prostate infections and PCa warrants further investigation.

Indexed as

allogeneic transplantationcryptococcusprostate cancerstem cell transplantationt-cell prolymphocytic leukemia

Identifiers

PMID38962597
PMCPMC11221391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.