Evidence map›Paper›PMID 38962496›Full record

ArticleNpj imaging2024

CohortFinder: an open-source tool for data-driven partitioning of digital pathology and imaging cohorts to yield robust machine-learning models.

Fan Fan, Georgia Martinez, Thomas DeSilvio, John Shin, Yijiang Chen, Jackson Jacobs, Bangchen Wang, Takaya Ozeki, Maxime W Lafarge, Viktor H Koelzer and 4 more

Abstract read
In one paragraph

Article in Npj imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Fan FanEmory University and Georgia Institute of Technology, Department of Biomedical Engineering, Atlanta, GA USA.
Georgia MartinezCase Western Reserve University, Department of Biomedical Engineering, Cleveland, OH USA.
Thomas DeSilvioCase Western Reserve University, Department of Biomedical Engineering, Cleveland, OH USA.
John ShinCase Western Reserve University, Department of Biomedical Engineering, Cleveland, OH USA.
Yijiang ChenCase Western Reserve University, Department of Biomedical Engineering, Cleveland, OH USA.
Jackson JacobsEmory University and Georgia Institute of Technology, Department of Biomedical Engineering, Atlanta, GA USA.
Bangchen WangDuke University, Department of Pathology, Division of AI & Computational Pathology, Durham, NC USA.
Takaya OzekiUniversity of Michigan, Department of Internal Medicine, Division of Nephrology, Ann Arbor, MI USA.
Maxime W LafargeUniversity Hospital of Zurich, University of Zurich, Department of Pathology and Molecular Pathology, Zurich, Switzerland.
Viktor H KoelzerUniversity Hospital of Zurich, University of Zurich, Department of Pathology and Molecular Pathology, Zurich, Switzerland.
Laura BarisoniDuke University, Department of Pathology, Division of AI & Computational Pathology, Durham, NC USA.
Anant MadabhushiEmory University and Georgia Institute of Technology, Department of Biomedical Engineering, Atlanta, GA USA.
Satish E ViswanathCase Western Reserve University, Department of Biomedical Engineering, Cleveland, OH USA.
Andrew JanowczykEmory University and Georgia Institute of Technology, Department of Biomedical Engineering, Atlanta, GA USA.

Funding

The Impact of COVID-19 on People Living with Rare Diseases and Their FamiliesU2CTR002818 · NCATS · CINCINNATI CHILDRENS HOSP MED CTR · PI Maurizio Macaluso · 2019 to 2026
$51.2M
Training Program in Clinical & Translationa Research in Human Glomerular DiseaseU54DK083912 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KRETZLER, MATTHIAS · 2009 to 2023
$20.3M
KPMP Kidney Mapping and Atlas Project (KMAP)U01DK133090 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jonathan Himmelfarb, Matthias Kretzler · 2022 to 2026
$10.4M
Interdisciplinary Biomedical Imaging Training ProgramT32EB007509 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI DAVID Lynn WILSON, Xin Yu · 2007 to 2026
$5.6M
Pathology CoreU54CA254566 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI GERSON, STANTON L., KIRENGA, BRUCE JAMES · 2020 to 2024
$5.0M
Computational Pathology of Proteinuric DiseasesR01DK118431 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI BARISONI, LAURA MARIACHIARA, HODGIN, JEFFREY BENTON · 2018 to 2025
$3.6M
OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP).R01NR019585 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI STILL, CAROLYN HARMON · 2021 to 2025
$3.4M
Oral Cavity Quantitative Histomorphometric Risk Classifier (OHbIC) in Oral Cavity Squamous Cell Carcinoma (OC-SCC)R01CA249992 · NCI · EMORY UNIVERSITY · PI LEWIS, JAMES, MADABHUSHI, ANANT · 2021 to 2025
$3.2M
Computerized histologic image predictor of cancer outcomeR01CA202752 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI FELDMAN, MICHAEL D, GANESAN, SHRIDAR · 2016 to 2020
$3.1M
Quantitative Histomorphometric Risk Classifier (QuHbIC) in HPV + Oropharyngeal CarcinomaR01CA220581 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI KOYFMAN, SHLOMO, LEWIS, JAMES · 2018 to 2023
$3.1M
Computerized Histologic Risk Predictor (CHiRP) for Early Stage Lung CancersR01CA216579 · NCI · EMORY UNIVERSITY · PI FU, PINGFU, LLOYD, MARK · 2018 to 2023
$3.1M
Prognostic and Predictive Digital Tissue Image Assay for Prostate CancerR01CA268287 · NCI · EMORY UNIVERSITY · PI GUPTA, SHILPA, LAL, PRITI · 2022 to 2025
$3.0M
BLRD VA I01 BX004121NCATS NIH HHS U2C TR002818NCI NIH HHS R01 CA202752NCI NIH HHS R01 CA208236NCI NIH HHS R01 CA216579NCI NIH HHS R01 CA220581NCI NIH HHS R01 CA249992NCI NIH HHS R01 CA257612NCI NIH HHS R01 CA268287NCI NIH HHS U01 CA239055NCI NIH HHS U01 CA248226NCI NIH HHS U01 CA269181NCI NIH HHS U54 CA254566NIBIB NIH HHS R43 EB028736NIBIB NIH HHS T32 EB007509NIDDK NIH HHS R01 DK118431NIDDK NIH HHS U01 DK133090NIDDK NIH HHS U54 DK083912NINR NIH HHS R01 NR019585NLM NIH HHS R01 LM013864
6 · The paper itself

Abstract

Batch effects (BEs) refer to systematic technical differences in data collection unrelated to biological variations whose noise is shown to negatively impact machine learning (ML) model generalizability. Here we release CohortFinder (http://cohortfinder.com), an open-source tool aimed at mitigating BEs via data-driven cohort partitioning. We demonstrate CohortFinder improves ML model performance in downstream digital pathology and medical image processing tasks. CohortFinder is freely available for download at cohortfinder.com.

Indexed as

Biomedical engineeringImage processing

Identifiers

PMID38962496
PMCPMC11216973

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.