Evidence map›Paper›PMID 38962495›Full record

ArticleJournal of tropical medicine2024

Prevalence of Hepatitis B Virus Infection in Tanzania: A Systematic Review and Meta-Analysis.

Semvua B Kilonzo, Igembe Nkandala, Ladius Rudovick, Hyasinta M Jaka, Mariam M Mirambo, Stephen E Mshana, Violet D Kajogoo, Elichilia R Shao

Abstract read
In one paragraph

Article in Journal of tropical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Semvua B KilonzoInternal Medicine Department, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.ORCID https://orcid.org/0000-0003-1197-9368
Igembe NkandalaInternal Medicine Department, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.ORCID https://orcid.org/0000-0002-1316-3955
Ladius RudovickInternal Medicine Department, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.ORCID https://orcid.org/0000-0003-2012-4054
Hyasinta M JakaInternal Medicine Department, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.ORCID https://orcid.org/0000-0001-8712-7976
Mariam M MiramboDepartment of Microbiology and Immunology, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.ORCID https://orcid.org/0000-0003-2313-3079
Stephen E MshanaDepartment of Microbiology and Immunology, Catholic University of Health and Allied Sciences, P.O. Box 1464, Mwanza, Tanzania.ORCID https://orcid.org/0000-0002-7526-6271
Violet D KajogooDepartment of Clinical Trials, Tanzania Diabetes Association, P.O. Box 65201, Dar es salaam, Tanzania.ORCID https://orcid.org/0000-0002-6122-3828
Elichilia R ShaoInternal Medicine Department, Kilimanjaro Christian Medical University College, P.O. Box 2240, Moshi, Tanzania.ORCID https://orcid.org/0000-0003-3618-2822

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methods: We systematically searched the PubMed, Web of Science, African Journals Online, Embase, Cochrane Library, and Google Scholar databases for studies conducted up to March 1, 2023, that estimated the prevalence of HBV in Tanzania based on HBV surface antigen measurements. The DerSimonian-Laird random effects model was used to estimate the overall prevalence of HBV with 95% confidence intervals (CIs). Potential sources of heterogeneity were also investigated. Results: Thirty-one studies with a total sample size of 37,988 were included in the meta-analysis. The overall average HBV prevalence estimate in Tanzania was 6.91% (95% CI = 5.18-8.86%). Subgroup analysis revealed the highest prevalence in the northern zone (9.32%, 95% CI; 2.24-20.36%), among the blood donors (18.72%, 95% CI: 17.43-20.05%) and among the community volunteers (8.76%, 95% CI: 4.55-14.15%). The lowest prevalence was observed in the lake zone at 4.66% (95% CI: 3.49-5.99) and in pregnant women at 4.72% (95% CI: 3.42-6.21). The overall between-study variability showed significant heterogeneity ( Conclusions: Our results showed that Tanzania is a country with moderately high HBV endemicity, with large interregional differences and significantly high numbers of HBV infections within the community. This underscores the need for immediate development of targeted prevention strategies and further epidemiological studies to better understand the pattern of the disease.

Identifiers

PMID38962495
PMCPMC11222000

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.