Evidence map›Paper›PMID 38962471›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2024

Improved Preservation of Rat Small Intestine Transplantation Graft by Introduction of Mesenchymal Stem Cell-Secreted Fractions.

Takumi Teratani, Yasuhiro Fujimoto, Yasunaru Sakuma, Naoya Kasahara, Masashi Maeda, Atsushi Miki, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama

Abstract read
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In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Takumi Teratani *Division of Translational Research, Jichi Medical University, Tochigi, Japan.
Yasuhiro Fujimoto *Transplantation Surgery, Nagoya University Hospital, Nagoya, Aichi, Japan.
Yasunaru SakumaDepartment of Surgery, Jichi Medical University, Tochigi, Japan.
Naoya KasaharaDivision of Translational Research, Jichi Medical University, Tochigi, Japan.
Masashi MaedaDivision of Translational Research, Jichi Medical University, Tochigi, Japan.
Atsushi MikiDepartment of Surgery, Jichi Medical University, Tochigi, Japan.
Alan Kawarai LeforDepartment of Surgery, Jichi Medical University, Tochigi, Japan.
Naohiro SataDepartment of Surgery, Jichi Medical University, Tochigi, Japan.
Joji KitayamaDivision of Translational Research, Jichi Medical University, Tochigi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Segmental grafts from living donors have advantages over grafts from deceased donors when used for small intestine transplantation. However, storage time for small intestine grafts can be extremely short and optimal graft preservation conditions for short-term storage remain undetermined. Secreted factors from mesenchymal stem cells (MSCs) that allow direct activation of preserved small intestine grafts. Freshly excised Luc-Tg LEW rat tissues were incubated in preservation solutions containing MSC-conditioned medium (MSC-CM). Preserved Luc-Tg rat-derived grafts were then transplanted to wild-type recipients, after which survival, injury score, and tight junction protein expression were examined. Luminance for each graft was determined using

Indexed as

Intestine, SmallMesenchymal Stem CellsOrgan PreservationRats, Inbred LewAdenosineAllopurinolAnimalsClaudin-3Culture Media, ConditionedGlutathioneGraft SurvivalInsulinMaleOrgan Preservation SolutionsRaffinoseRatsAdenosineAllopurinolClaudin-3Culture Media, ConditionedGlutathioneInsulinOrgan Preservation SolutionsRaffinoseUniversity of Wisconsin-lactobionate solutionZonula Occludens-1 Proteingraft survivalmesenchymal stem cellspreservationsmall intestinetransplantation

Identifiers

PMID38962471
PMCPMC11219629

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.