ArticleGeneral psychiatry2024
Temporal trends and cohort variations of gender-specific major depressive disorders incidence in China: analysis based on the age-period-cohort-interaction model.
Article in General psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed.
- Global, regional, and national tuberculosis burden associated with six suboptimal dietary exposures from 1990 to 2021: a comparative risk assessment based on the Global Burden of Disease Study 2021.Journal of thoracic disease · 2026Article
- Associations between anxiety, somatic pain and sleep disturbances in major depressive disorder and chronic pain: A cross-sectional study with gender-specific insights.General psychiatry · 2026Article
- The Association Between Body Image and Depression: Historical Evolution and Recent Research Progress.Psychology research and behavior management · 2026Review
- Mitochondrial dysfunction, a new marker warning of neuropsychiatric disorder risk: evidence from genetics and epidemiology.Annals of general psychiatry · 2025Article
- Temporal trends and machine learning prediction of depressive symptoms among Chinese middle-aged and elderly individuals: a national cohort study.BMC public health · 2025Article
- Incidence and prevalence of dysthymia among young adults in China, 1990-2021, with forecasts to 2046: an age-period-cohort analysis of the Global Burden of Disease Study 2021.BMC psychiatry · 2025Article
- Global, regional, and national burden and trends of depressive disorders among women of childbearing age from 1990 to 2021: insights from GBD 2021.Frontiers in psychology · 2025Article
- Guidelines for the diagnosis and treatment of depressive disorders by integrating Chinese and Western medicine (English edition).General psychiatry · 2025Article
- Family Dynamics and Depression Among Children: An Integrative Review of Theoretical Models and Attachment-Based Interventions.Psychology research and behavior management · 2025Review
- Preliminary network analysis of suicide risk and psychosocial factors in Chinese adults and older adults with depression: a cross-sectional study.Frontiers in psychiatry · 2025Article
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Abstract
Background: Major depressive disorders (MDDs) impose substantial burdens on individuals and society; however, further detailed analysis is still needed for its long-term trends. Aims: This study aimed to analyse the gender-specific temporal trends and cohort variations of MDD incidence among Chinese residents over the past three decades. Methods: Employing the age-period-cohort-interaction model and leveraging data from the Global Burden of Disease Study 2019, this research identified and analysed incidence trends of MDD among Chinese males and females aged 5-94 years from 1990 to 2019 across three dimensions, encompassing age, period and birth cohort. Results: The analysis reveals age-related effects, indicating heightened MDD risk among adolescents and older adults. Specifically, individuals entering the older adulthood at the age of 65-69 significantly increased the risk of MDD by 64.9%. People aged 90-94 years witnessed a 105.4% increase in MDD risk for the overall population, with females and males in this age group experiencing a 75.1% and 103.4% increase, respectively. In terms of period effects, the risk of MDD displayed a decline from 1990 to 1994, followed by a rebound in 2008. Cohort effects demonstrated diverse generational patterns, with generation I and generation III manifesting opposing 'age-as-level' trends. Generation II and generation IV exhibited 'cumulative disadvantage' and 'cumulative advantage' patterns, respectively. Age effects indicated an overall higher risk of MDD incidence in females, while cohort effects showed greater variations of MDD incidence among females. Conclusions: The study underscores the substantial effects of age, period and cohort on MDD across genders in China. Priority interventions targeting vulnerable populations, including children, adolescents, older adults, females and the post-millennium birth cohort, are crucial to mitigate the impact of MDD.
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