ArticleHealth SA = SA Gesondheid2024
Interaction of social support and depressive symptoms on antiretroviral therapy adherence among people living with HIV in South Africa.
Article in Health SA = SA Gesondheid, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Prevalence of Depression Among People Living with HIV on Antiretroviral Therapy in Africa: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2025Review
- Developing a Culturally Informed Peer Support Model for Men Who Have Sex With Men Living With HIV: A Qualitative Study in Indonesia.Journal of the International Association of Providers of AIDS CareArticle
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Authors and funding
2 authors.
Funding
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Abstract
Background: Depression consistently emerges as a significant predictor of poor antiretroviral therapy (ART) adherence among adult people living with human immunodeficiency virus (PLHIV). However, a gap exists regarding how social support and depressive symptoms can interact to influence ART adherence among adult PLHIV in South Africa (SA). Aim: To investigate the interaction between social support and depressive symptoms on ART adherence among adult PLHIV. Setting: A tertiary hospital in Durban, KwaZulu-Natal province of SA. Methods: Utilising a quantitative cross-sectional research design along with time location sampling technique (TLS); the study recruited 201 adult patients enrolled in an ART programme. Results: The results indicated that depressive symptoms were significantly associated with ART adherence with and without the interaction (B = -0.105; odds ratios [OR] 0.901; 95% confidence intervals [CI] = 0.827, 0.981; Conclusion: Based on the results, depressive symptoms significantly influenced ART adherence. However, social support did not buffer the adverse effects of clinical depression associated with poor ART adherence. Contribution: This study provides an evidence-based approach to address gaps in the mental health and social well-being of PLHIV in the context of ART adherence.
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