ArticlePlastic and reconstructive surgery. Global open2024
Outcomes of Biodegradable Temporizing Matrix for Soft Tissue Reconstruction of the Hand and Extremities.
Article in Plastic and reconstructive surgery. Global open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biodegradable Temporising matrix in the reconstruction of complex wounds: A systematic review and meta-analysis.International wound journal · 2024Pooled it
- Beyond Early Excision and Grafting: A Perspective on Tissue-Preserving and Regenerative Topical Burn Wound Care.Journal of clinical medicine · 2026Article
- Successful Limb Salvage Using Staged Applications of a Fish-Skin Xenograft (Kerecis) in a Heel Pad Degloving Injury: A Case Report.Journal of orthopaedic case reports · 2026Article
- Proximal Humerus Ewing Sarcoma: Technical Challenges and Strategies for Bone Defect Reconstruction.Journal of orthopaedic case reports · 2026Article
- Long-term Outcomes of Neonatal Hand Sarcoma Reconstruction With Integra and Full-thickness Skin Grafting.Plastic and reconstructive surgery. Global open · 2026Article
- Two-stage Reconstruction of Acute Extensive Third-degree Burn Using Biodegradable Temporizing Matrix (NovoSorb BTM).Plastic and reconstructive surgery. Global open · 2026Article
- Early Experience With Utilizing Biodegradable Temporizing Matrix (BTM) for Complex Pediatric Wound Reconstruction.Plastic surgery (Oakville, Ont.) · 2026Article
- Single stage reconstruction of the right thumbnail with Novosorb® Biodegradable Temporizing Matrix (BTM) following massive glomus tumor resection.JPRAS open · 2026Article
- The Role and Efficacy of NovoSorb Biodegradable Temporizing Matrix in Complex Reconstructive Wounds: A Systematic Review.Plastic and reconstructive surgery. Global open · 2026Article
- The Role of Biodegradable Temporizing Matrix in Hand Surgery for Paediatric Recessive Dystrophic Epidermolysis Bullosa.Journal of clinical medicine · 2026Article
- Biodegradable Temporizing Matrix Use Over an Exposed Lower Limb Joint.Plastic and reconstructive surgery. Global open · 2025Article
- The Role of Biodegradable Temporizing Matrix in Paediatric Reconstructive Surgery.Journal of clinical medicine · 2025Article
- Advanced Wound Care Strategies in Patients with NSTIs.Journal of clinical medicine · 2025Review
- The Reconstruction of Various Complex Full-Thickness Skin Defects with a Biodegradable Temporising Matrix: A Case Series.European burn journal · 2025Article
- Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: NovoSorb biodegradable temporizing matrix (BTM) is a novel, bilayer, synthetic skin substitute made of biodegradable polyurethane foam covered with a sealing membrane. BTM has demonstrated excellent outcomes in burn literature; however, few studies have been published for hand and extremity soft tissue reconstruction. Methods: All patients who underwent extremity reconstruction with BTM from 2018 to 2023 were reviewed. Demographics, presentations, and clinical outcomes were recorded. Results: A total of 86 cases from 54 patients (53.7% pediatric; age range: 0-81 years) were included. Common indications included trauma (36%), infection (18.6%), and malignancy (11.6%). BTM was placed over exposed tendon (38.4%), bone (19%), joints (12.8%), nerves (8.1%), and/or blood vessels (7%). BTM served as temporary wound coverage in 26 cases. Complications included hematoma (8.1%), infection (4.7%), and spontaneous delamination (4.7%). Wound closure was successfully obtained without flap use in 93.3%. Poor BTM take was associated with peripheral vascular disease, hypertension, immunosuppression, and BTM hematoma and infection (<0.05). Conclusion: This study contributes to the growing body of evidence favoring BTM use in challenging reconstructive cases. Although prospective comparative studies are forthcoming, BTM likely has broad applications in reconstructive surgery.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.