Evidence map›Paper›PMID 38962051›Full record

ArticleInternational cancer conference journal2024

An underrecognized association: immune checkpoint inhibitor-related aortitis, a case report with the review of the literature.

Reşit Yıldırım, Aida Shikhaliyeva, Hüseyin İçer, Hakan Deveci, Emre Entok, Döndü Üsküdar Cansu, Cengiz Korkmaz

Abstract read
In one paragraph

Article in International cancer conference journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Drug-associated abdominal aortitis and retroperitoneal fibrosis after treatment with nivolumab.Journal of vascular surgery cases and innovative techniques · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Reşit YıldırımDivision of Rheumatology, Eskişehir Osmangazi University School of Medicine, 26480 Eskisehir, Turkey.ORCID 0000-0003-4040-0212
Aida ShikhaliyevaDepartment of Internal Medicine, Eskişehir Osmangazi University School of Medicine, Eskisehir, Turkey.ORCID 0000-0003-1557-8414
Hüseyin İçerDepartment of Internal Medicine, Eskişehir Osmangazi University School of Medicine, Eskisehir, Turkey.ORCID 0000-0002-1134-4541
Hakan DeveciDivision of Nuclear Medicine, Department of Radiology, Eskişehir Osmangazi University School of Medicine, Eskisehir, Turkey.ORCID 0000-0003-2642-3557
Emre EntokDivision of Nuclear Medicine, Department of Radiology, Eskişehir Osmangazi University School of Medicine, Eskisehir, Turkey.ORCID 0000-0002-6164-6361
Döndü Üsküdar CansuDivision of Rheumatology, Eskişehir Osmangazi University School of Medicine, 26480 Eskisehir, Turkey.ORCID 0000-0001-6543-3905
Cengiz KorkmazDivision of Rheumatology, Eskişehir Osmangazi University School of Medicine, 26480 Eskisehir, Turkey.ORCID 0000-0003-2679-0699

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune-checkpoint inhibitors (ICIs) are considered as the novel treatment modality in certain cancers. They may soon be used widely even as the first-line option for cancer treatment due to their remarkable efficacies and impacts on survival rates, particularly in cases of advanced metastatic cancer. Of note, these agents might unveil new autoimmune diseases as well as causing flare-ups of a pre-existing autoimmune disease. Data in this field have been accumulated during recent years. Early detection and a collaborative approach are, therefore, crucial in the management of a patient who presents with any of these conditions. Herein, we report a patient with a diagnosis of metastatic renal cell cancer presented with vasculitis involvement in the aorta during nivolumab treatment. Our aim with this case is to increase the awareness of ICI-related vasculitis involvement among rheumatologists in the light of literature.

Indexed as

AortitisCancer treatmentImmune checkpoint inhibition

Identifiers

PMID38962051
PMCPMC11217252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.