Evidence map›Paper›PMID 38961232›Full record

ArticleMolecular psychiatry2025

Influenza A virus during pregnancy disrupts maternal intestinal immunity and fetal cortical development in a dose- and time-dependent manner.

Ashley M Otero, Meghan G Connolly, Rafael J Gonzalez-Ricon, Selena S Wang, Jacob M Allen, Adrienne M Antonson

Abstract read
In one paragraph

Article in Molecular psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Mild SARS-CoV-2 maternal infection in mice induces transient offspring neurodevelopmental aberrance.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Review
  8. Review
  9. Microglia as critical mediators linking perinatal immune stress to mental health trajectories.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ashley M OteroNeuroscience Program, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Meghan G ConnollyNeuroscience Program, University of Illinois Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0003-0654-6330
Rafael J Gonzalez-RiconNeuroscience Program, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Selena S WangDepartment of Animal Sciences, University of Illinois Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0001-5417-3546
Jacob M AllenDepartment of Kinesiology and Community Health, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Adrienne M AntonsonNeuroscience Program, University of Illinois Urbana-Champaign, Urbana, IL, USA. aantnsn2@illinois.edu.ORCID 0000-0001-5698-5353

Funding

Roy J. Carver Charitable Trust (Carver Charitable Trust) 23-5683
6 · The paper itself

Abstract

Epidemiological studies link exposure to viral infection during pregnancy, including influenza A virus (IAV) infection, with increased incidence of neurodevelopmental disorders (NDDs) in offspring. Models of maternal immune activation (MIA) using viral mimetics demonstrate that activation of maternal intestinal T helper 17 (T

Indexed as

Influenza A virusAnimalsBrainCerebral CortexCytokinesDisease Models, AnimalFemaleFetal DevelopmentFetusInterleukin-17IntestinesMacrophagesMiceMice, Inbred C57BLMicrogliaNeurodevelopmental DisordersCytokinesInterleukin-17

Identifiers

PMID38961232
PMCPMC11649561

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.